关键词: COVID-19 Unwanted effects / adverse reactions Vaccination/immunisation

Mesh : Female Humans Anti-Bacterial Agents Axilla Biological Transport COVID-19 COVID-19 Vaccines / adverse effects Fever / chemically induced Vaccination / adverse effects Adult

来  源:   DOI:10.1136/bcr-2022-253671   PDF(Pubmed)

Abstract:
A woman in her 40s, with a known history of fibromyalgia, presented with high-grade fever and constitutional symptoms occurring 5 days following vaccination with Oxford-AstraZeneca COVID-19 vaccine (ChAdOx1). Her inflammatory markers and neutrophil count were found to be elevated and as such, she was started on antibiotics. Despite treatment, markers remained elevated and temperature spikes persisted for another 4 weeks before these symptoms subsided, and her blood tests normalised. All investigations taken in the interim were negative, with no source being identified for the fever. As a result, a positron emission tomography scan was performed to attempt to localise the source of these symptoms. This revealed low-to-moderate grade lymph node tracer uptake above and below the diaphragm most pervasive in the right axilla, with uptake in the right arm corresponding with the site of vaccination.
摘要:
一个40多岁的女人,有已知的纤维肌痛病史,在Oxford-AstraZenecaCOVID-19疫苗(ChAdOx1)接种5天后出现高热和全身症状。发现她的炎症标志物和中性粒细胞计数升高,因此,她开始服用抗生素.尽管治疗,在这些症状消退之前,标记物仍然升高,温度峰值持续了另外4周,她的血液检查恢复正常了.在此期间进行的所有调查均为阴性,没有发现发烧的来源。因此,进行了正电子发射断层扫描以尝试定位这些症状的来源。这显示右腋窝中最普遍的膈肌上方和下方的低至中度淋巴结示踪剂摄取,右臂的摄取与疫苗接种部位相对应。
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