Abstract：
This document is an update of the multidisciplinary document HEMOMAS, published in 2016 with the endorsement of the Spanish Scientific Societies of Anaesthesiology (SEDAR), Intensive Care (SEMICYUC) and Thrombosis and Haemostasis (SETH). The aim of this document was to review and update existing recommendations on the management of massive haemorrhage. The methodology of the update was based on several elements of the ADAPTE method by searching and adapting guidelines published in the specific field of massive bleeding since 2014, plus a literature search performed in PubMed and EMBASE from January 2014 to June 2021. Based on the review of 9 guidelines and 207 selected articles, the 47 recommendations in the original article were reviewed, maintaining, deleting, or modifying each of them and the accompanying grades of recommendation and evidence. Following a consensus process, the final wording of the article and the resulting 41 recommendations were approved by all authors.
摘要：
本文件是多学科文件HEMOMAS的更新，2016年出版，获得了西班牙麻醉学科学学会（SEDAR）的认可，重症监护（SEMICYUC）和血栓形成和止血（SETH）。本文件的目的是审查和更新关于大出血管理的现有建议。更新的方法基于ADAPTE方法的几个要素，通过搜索和调整自2014年以来在大出血的特定领域发布的指南，以及2014年1月至2021年6月在PubMed和EMBASE进行的文献检索。根据对9条准则和207条精选文章的审查，审查了原始文章中的47项建议，维护,删除,或修改它们中的每一个以及随附的推荐和证据等级。在达成共识之后，文章的最终措辞和由此产生的41条建议得到了所有作者的认可.
