关键词: antiseizure medications lamotrigine steven-johnson syndrome (sjs) toxic epidermal necrolysis (ten) valproic acid

来  源:   DOI:10.7759/cureus.41267   PDF(Pubmed)

Abstract:
Steven-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are part of a spectrum of severe cutaneous adverse reactions, secondary to infections or drug-induced. Although the use of antiseizure medications (ASMs) is a risk factor for the development of SJS/TEN, primary care physicians are not familiar with these cases in some countries. We report a case of SJS associated with ASMs in a nine-year-old girl with a history of difficult-to-control epilepsy, who required adjustment and change in medications.
摘要:
Steven-Johnson综合征(SJS)和中毒性表皮坏死松解症(TEN)是一系列严重皮肤不良反应的一部分,继发于感染或药物诱导。尽管使用抗癫痫药物(ASM)是SJS/TEN发展的危险因素,在一些国家,初级保健医生不熟悉这些病例。我们报告了一例SJS与ASM相关的9岁女孩,有难以控制的癫痫史,他们需要调整和改变药物。
公众号