PDF(Pubmed)
Abstract：
: To study the prevalence of pseudoexfoliation syndrome (PEX) in diabetics with senile cataracts and compare it to the prevalence in nondiabetic control group.
: Two hundred and fifty diabetics and 250 nondiabetics (age and sex matched) were evaluated for PEX deposition.
: Chi-squared test was employed, and a P value < 0.05 was considered significant. In the PEX group, most patients belonged to the age group of 60-70 years (55.17%). Out of 18 patients with PEX, 11 (61.1%) showed bilaterality. There was a higher frequency of raised intraocular pressure (IOP; >20 mmHg) in PEX eyes (10.3%) than in the non-PEX eyes (5.9%). The PEX group had a higher number of eyes with cup-to-disc ratio (CDR) >0.6 (11.12%) than the non-PEX group (4.32%). Nuclear cataracts were more frequent in PEX eyes than non-PEX eyes, whereas PSC and mature cataracts were more prevalent in the non-PEX group. Most eyes had PEX deposition on the anterior lens capsule and pupillary margin. Of the 500 study eyes corresponding to the diabetic group, 418 had cataracts (rest pseudophakic), of which 28 had pseudoexfoliation, accounting for 6.7% of the total. In the nondiabetic control group comprising 500 eyes, 430 had senile cataracts (rest pseudophakic), of which 105 had PEX deposition, accounting for 24.4% of the total.
: According to our findings, diabetics have a lower prevalence of PEX than nondiabetics. Few such studies have been conducted so far, and none have been conducted in the Indian population.
: Two hundred and fifty diabetics and 250 nondiabetics (age and sex matched) were evaluated for PEX deposition.
: Chi-squared test was employed, and a P value < 0.05 was considered significant. In the PEX group, most patients belonged to the age group of 60-70 years (55.17%). Out of 18 patients with PEX, 11 (61.1%) showed bilaterality. There was a higher frequency of raised intraocular pressure (IOP; >20 mmHg) in PEX eyes (10.3%) than in the non-PEX eyes (5.9%). The PEX group had a higher number of eyes with cup-to-disc ratio (CDR) >0.6 (11.12%) than the non-PEX group (4.32%). Nuclear cataracts were more frequent in PEX eyes than non-PEX eyes, whereas PSC and mature cataracts were more prevalent in the non-PEX group. Most eyes had PEX deposition on the anterior lens capsule and pupillary margin. Of the 500 study eyes corresponding to the diabetic group, 418 had cataracts (rest pseudophakic), of which 28 had pseudoexfoliation, accounting for 6.7% of the total. In the nondiabetic control group comprising 500 eyes, 430 had senile cataracts (rest pseudophakic), of which 105 had PEX deposition, accounting for 24.4% of the total.
: According to our findings, diabetics have a lower prevalence of PEX than nondiabetics. Few such studies have been conducted so far, and none have been conducted in the Indian population.
摘要：
■：研究糖尿病合并老年性白内障患者中假性剥脱综合征（PEX）的患病率，并将其与非糖尿病对照组的患病率进行比较。
■：评估了250名糖尿病患者和250名非糖尿病患者（年龄和性别匹配）的PEX沉积。
■：采用卡方检验，P值<0.05被认为是显著的。在PEX组中，大多数患者属于60-70岁年龄组(55.17%)。在18名PEX患者中，11例（61.1%）呈双侧性。PEX眼（10.3％）的眼内压升高（IOP；>20mmHg）的频率高于非PEX眼（5.9％）。PEX组的眼杯盘比(CDR)>0.6(11.12%)高于非PEX组(4.32%)。核性白内障在PEX眼中比非PEX眼中更常见，而PSC和成熟白内障在非PEX组中更为普遍。大多数眼睛在晶状体前囊和瞳孔边缘有PEX沉积。在对应于糖尿病组的500只研究眼睛中，418患有白内障（其余假晶状体），其中28人出现假性剥脱，占总数的6.7%。在包括500只眼的非糖尿病对照组中，430人患有老年性白内障（其余假晶状体），其中105个有PEX沉积，占总数的24.4%。
■：根据我们的发现，糖尿病患者的PEX患病率低于非糖尿病患者。到目前为止，很少进行过这样的研究，没有在印度人口中进行过。
■：评估了250名糖尿病患者和250名非糖尿病患者（年龄和性别匹配）的PEX沉积。
■：采用卡方检验，P值<0.05被认为是显著的。在PEX组中，大多数患者属于60-70岁年龄组(55.17%)。在18名PEX患者中，11例（61.1%）呈双侧性。PEX眼（10.3％）的眼内压升高（IOP；>20mmHg）的频率高于非PEX眼（5.9％）。PEX组的眼杯盘比(CDR)>0.6(11.12%)高于非PEX组(4.32%)。核性白内障在PEX眼中比非PEX眼中更常见，而PSC和成熟白内障在非PEX组中更为普遍。大多数眼睛在晶状体前囊和瞳孔边缘有PEX沉积。在对应于糖尿病组的500只研究眼睛中，418患有白内障（其余假晶状体），其中28人出现假性剥脱，占总数的6.7%。在包括500只眼的非糖尿病对照组中，430人患有老年性白内障（其余假晶状体），其中105个有PEX沉积，占总数的24.4%。
■：根据我们的发现，糖尿病患者的PEX患病率低于非糖尿病患者。到目前为止，很少进行过这样的研究，没有在印度人口中进行过。
