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Abstract：
UNASSIGNED: The World Health Organization (WHO) has identified viral hepatitis, caused by hepatitis B virus (HBV) and hepatitis C virus (HCV), as one of the main global public health issues. People who work in the collection of waste materials, from either household or medical environments, are at greatest risk.
UNASSIGNED: To determine the prevalence of and factors associated with HBV and HCV among medical and domestic waste handlers in Northeast Ethiopia.
UNASSIGNED: A comparative cross-sectional study was conducted from January to April 2021 at selected healthcare facilities and municipal settings in Dessie town, Northeast Ethiopia. The sample size was determined using a double population proportion formula, and a simple random sampling technique was employed to select 70 individuals in the medical waste handlers (MWHs) group and 206 in the domestic waste handlers (DWHs) group. Five milliliters of venous blood was collected from each participant and tested for HBV and HCV using an enzyme-linked immunosorbent assay. Data were analyzed using SPSS version 23; the prevalence was computed, Fisher\'s exact test was used, and logistic regression was applied.
UNASSIGNED: A total of 276 study participants were enrolled and the overall seroprevalence of hepatitis virus was 5.1%. The seroprevalence of HBV infection among MWHs and DWHs was 8.6% and 1.9%, respectively. The overall seroprevalence of HCV infections among MWHs and DWHs was 4.3% and 0.5%, respectively. Medical waste handling, having a history of needle stick injury, and not using personal protective equipment were factors significantly associated with HBV infection.
UNASSIGNED: The overall seroprevalence of viral hepatitis was high. The prevalence of HBV infection among MWHs was in line with the high endemicity classification of the WHO, and there was a significant difference in prevalence between DWHs and MWHs. Both groups of waste handlers should receive proper attention to protect them from HBV and HCV infection.
UNASSIGNED: To determine the prevalence of and factors associated with HBV and HCV among medical and domestic waste handlers in Northeast Ethiopia.
UNASSIGNED: A comparative cross-sectional study was conducted from January to April 2021 at selected healthcare facilities and municipal settings in Dessie town, Northeast Ethiopia. The sample size was determined using a double population proportion formula, and a simple random sampling technique was employed to select 70 individuals in the medical waste handlers (MWHs) group and 206 in the domestic waste handlers (DWHs) group. Five milliliters of venous blood was collected from each participant and tested for HBV and HCV using an enzyme-linked immunosorbent assay. Data were analyzed using SPSS version 23; the prevalence was computed, Fisher\'s exact test was used, and logistic regression was applied.
UNASSIGNED: A total of 276 study participants were enrolled and the overall seroprevalence of hepatitis virus was 5.1%. The seroprevalence of HBV infection among MWHs and DWHs was 8.6% and 1.9%, respectively. The overall seroprevalence of HCV infections among MWHs and DWHs was 4.3% and 0.5%, respectively. Medical waste handling, having a history of needle stick injury, and not using personal protective equipment were factors significantly associated with HBV infection.
UNASSIGNED: The overall seroprevalence of viral hepatitis was high. The prevalence of HBV infection among MWHs was in line with the high endemicity classification of the WHO, and there was a significant difference in prevalence between DWHs and MWHs. Both groups of waste handlers should receive proper attention to protect them from HBV and HCV infection.
摘要：
■世界卫生组织（WHO）已经确定了病毒性肝炎，由乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV），作为全球主要的公共卫生问题之一。从事废料收集工作的人，无论是家庭还是医疗环境，风险最大。
■确定埃塞俄比亚东北部医疗和生活废物处理人员中HBV和HCV的患病率和相关因素。
■于2021年1月至4月在Dessie镇的选定医疗机构和市政环境中进行了比较性的横断面研究，埃塞俄比亚东北部。样本量是使用双人口比例公式确定的，并采用简单的随机抽样技术在医疗废物处理人员（MWHs）组中选择70个人，在生活废物处理人员（DHHs）组中选择206个人。从每个参与者收集5毫升静脉血，并使用酶联免疫吸附测定法测试HBV和HCV。使用SPSS版本23分析数据；计算患病率，使用费希尔的精确检验，并应用逻辑回归。
■共有276名研究参与者入组，肝炎病毒的总血清阳性率为5.1%。HBV感染在MWH和DWH之间的血清阳性率为8.6％和1.9％，分别。MWH和DWH中HCV感染的总体血清阳性率分别为4.3％和0.5％，分别。医疗废物处理，有针刺伤的病史，和不使用个人防护设备是与HBV感染显著相关的因素。
■病毒性肝炎的总体血清阳性率很高。MWH中HBV感染的患病率符合WHO的高地方性分类，DWHs和MWHs的患病率存在显着差异。两组废物处理人员都应得到适当的关注，以保护他们免受HBV和HCV感染。
■确定埃塞俄比亚东北部医疗和生活废物处理人员中HBV和HCV的患病率和相关因素。
■于2021年1月至4月在Dessie镇的选定医疗机构和市政环境中进行了比较性的横断面研究，埃塞俄比亚东北部。样本量是使用双人口比例公式确定的，并采用简单的随机抽样技术在医疗废物处理人员（MWHs）组中选择70个人，在生活废物处理人员（DHHs）组中选择206个人。从每个参与者收集5毫升静脉血，并使用酶联免疫吸附测定法测试HBV和HCV。使用SPSS版本23分析数据；计算患病率，使用费希尔的精确检验，并应用逻辑回归。
■共有276名研究参与者入组，肝炎病毒的总血清阳性率为5.1%。HBV感染在MWH和DWH之间的血清阳性率为8.6％和1.9％，分别。MWH和DWH中HCV感染的总体血清阳性率分别为4.3％和0.5％，分别。医疗废物处理，有针刺伤的病史，和不使用个人防护设备是与HBV感染显著相关的因素。
■病毒性肝炎的总体血清阳性率很高。MWH中HBV感染的患病率符合WHO的高地方性分类，DWHs和MWHs的患病率存在显着差异。两组废物处理人员都应得到适当的关注，以保护他们免受HBV和HCV感染。
