关键词: Bacterial keratitis Corneal graft Corneal melting Corneal perforation DALK TutoPatch

来  源:   DOI:10.1016/j.ajoc.2023.101885   PDF(Pubmed)

Abstract:
UNASSIGNED: Corneal perforation due to severe melting is a very dangerous, sight-threatening condition requiring immediate management due to the high risk of endophthalmitis and critical hypotony. In the case of perforated corneal grafts, retransplantation is usually postponed to avoid the detrimental effects of inflammation on the new graft. We describe the first case of the use of a TutoPatch graft for emergency replacement of a lamellar graft perforation over acute infectious total melting.
UNASSIGNED: A 42-year-old male patient presented to the Emergency Department with pain in the left eye, which was red photophobic. He had been treated with bilateral deep anterior lamellar keratoplasty (DALK) for advanced keratoconus 5 years previously and had been experiencing recurrent corneal ulcers in the left eye within the last 8 months. Clinical examination documented corneal perforation over acute infectious melting involving the total graft surface in the left eye. The infected graft was removed along with the perforated infected residual Descemet membrane, and a double-layer TutoPatch covering was sutured to the host\'s margin with 10.0 nylon. The covering was left in place for three weeks, allowing the patient to undergo retransplant three weeks later without complications.
UNASSIGNED: TutoPatch covering can be safely used as an easy-to-preserve emergency material for a temporary bridge to retransplantation in large acute infectious corneal melting.
摘要:
角膜穿孔由于严重融化是非常危险的,由于眼内炎和严重的低眼压的高风险,危及视力的疾病需要立即治疗。在角膜移植穿孔的情况下,通常推迟再移植,以避免炎症对新移植物的有害影响。我们描述了使用TutoPatch移植物紧急替换急性感染性完全融化的层状移植物穿孔的第一例。
一名42岁的男性患者因左眼疼痛被送往急诊科,这是红色的憎光。5年前,他曾接受双侧深板层角膜移植术(DALK)治疗晚期圆锥角膜,并且在过去8个月内左眼复发性角膜溃疡。临床检查记录了急性感染性融化引起的角膜穿孔,涉及左眼的整个移植物表面。被感染的移植物与穿孔的被感染的残留Descemet膜一起被移除,用10.0尼龙将双层TutoPatch覆盖物缝合到宿主的边缘。覆盖物放置了三个星期,允许患者在三周后接受再次移植而没有并发症。
TutoPatch覆盖物可以安全地用作易于保存的紧急材料,用于在大型急性感染性角膜融化中进行临时桥梁再移植。
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