PDF(Pubmed)
Abstract：
Effective control of foodborne pathogen contamination is a significant challenge to the food industry, but the development of new antibacterial nanotechnologies offers new opportunities. Notably, selenium nanoparticles have been extensively studied and successfully applied in various food fields. Selenium nanoparticles act as food antibacterial agents with a number of benefits, including selenium as an essential trace element in food, prevention of drug resistance induction in foodborne pathogens, and improvement of shelf life and food storage conditions. Compared to physical and chemical methods, biogenic selenium nanoparticles (Bio-SeNPs) are safer and more multifunctional due to the bioactive molecules in Bio-SeNPs. This review includes a summarization of (1) biosynthesized of Bio-SeNPs from different sources (plant extracts, fungi and bacteria) and their antibacterial activity against various foodborne bacteria; (2) the antibacterial mechanisms of Bio-SeNPs, including penetration of cell wall, damage to cell membrane and contents leakage, inhibition of biofilm formation, and induction of oxidative stress; (3) the potential antibacterial applications of Bio-SeNPs as food packaging materials, food additives and fertilizers/feeds for crops and animals in the food industry; and (4) the cytotoxicity and animal toxicity of Bio-SeNPs. The related knowledge contributes to enhancing our understanding of Bio-SeNP applications and makes a valuable contribution to ensuring food safety.
摘要：
有效控制食源性致病菌污染是食品工业面临的重大挑战,但是新的抗菌纳米技术的发展提供了新的机会。值得注意的是,硒纳米颗粒已被广泛研究并成功应用于各种食品领域。硒纳米颗粒作为食品抗菌剂有很多好处，包括硒作为食物中必需的微量元素，预防食源性病原体的耐药性诱导，以及改善保质期和食品储存条件。与物理和化学方法相比，生物硒纳米颗粒（Bio-SeNPs）由于Bio-SeNPs中的生物活性分子而更安全，更多功能。这篇综述包括(1)生物合成不同来源的Bio-SeNPs(植物提取物，真菌和细菌）及其对各种食源性细菌的抗菌活性；（2）Bio-SeNP的抗菌机制，包括穿透细胞壁，细胞膜损伤和内容物渗漏，抑制生物膜的形成，(3)Bio-SeNPs作为食品包装材料的潜在抗菌应用,食品工业中用于作物和动物的食品添加剂和肥料/饲料;和(4)Bio-SeNP的细胞毒性和动物毒性。相关知识有助于增强我们对Bio-SeNP应用的理解，并为确保食品安全做出宝贵贡献。
