PDF(Pubmed)
Abstract：
Nasal osteoblastoma (OB) is a rare and locally aggressive osteogenic tumor that has rarely been reported, and there is a lack of effective evidence data for its diagnosis and treatment. In this study, we report a 31-year-old female patient who presented with nasal congestion and associated progressive painless swelling of the left maxillofacial region. A preoperative computed tomography (CT) examination of the paranasal sinuses was performed, and based on the imaging presentation, the surgeon was unable to differentiate between OB, osteoid osteoma (OO), fibrous dysplasia of bone (FDB) and osteoblastic fibroma (OF). After excluding contraindications to surgery, the patient underwent nasal endoscopic excision of the left nasal mass, which was found to be gravel-like and difficult to remove cleanly during the operation. The mass was brittle and bled easily, resulting in inadequate exposure of the operative field, prolonged operation time, and substantial intraoperative blood loss. This indicates that definite preoperative diagnosis (biopsy of deeper parts of the mass is recommended) and appropriate preoperative preparations (e.g., preoperative angiography and embolization, adequate blood preparation) are very important. The intraoperative frozen and postoperative pathological results clearly identified the tumor as OB. No local recurrence of the tumor was observed at the 11-month postoperative follow-up.
摘要：
鼻骨母细胞瘤(OB)是一种罕见的局部侵袭性成骨性肿瘤，至今鲜有报道。并且缺乏有效的诊断和治疗证据数据。在这项研究中,我们报告了1例31岁女性患者,表现为鼻塞和相关的左侧颌面部进行性无痛性肿胀.进行了鼻旁窦的术前计算机断层扫描（CT）检查，根据成像演示，外科医生无法区分OB，骨样骨瘤（OO），骨纤维发育不良（FDB）和成骨细胞纤维瘤（OF）。排除手术禁忌症后，患者接受了鼻内镜下左侧鼻肿块切除术，它被发现是砾石状的，在操作过程中很难清除干净。质量很脆，容易流血，导致手术区域暴露不足，延长操作时间，术中大量失血。这表明明确的术前诊断（建议对肿块的较深部分进行活检）和适当的术前准备（例如，术前血管造影和栓塞，充足的血液准备)非常重要。术中冰冻及术后病理结果明确肿瘤为OB。术后随访11个月，未观察到肿瘤局部复发。
