PDF(Pubmed)
Abstract：
Constipation is common in children and can significantly affect quality of life. Prebiotics are reportedly helpful for constipation in adults, but few studies have examined their use in young children. In this study, the effect of 1-kestose (kestose), which has excellent bifidobacterial growth properties, on constipation in kindergarten children (n = 11) was compared with that of maltose (n = 12) in a randomized, double-blind study. Three grams of kestose per day for 8 weeks did not affect stool properties, but significantly increased the number of defecations per week (Median; 3 → 4 times/week, p = 0.017, effect size = 0.53). A significant decrease in Intestinibacter, a trend toward increased bifidobacteria, and a trend toward decreased Clostridium sensu stricto were observed after kestose ingestion, while concentrations of short-chain fatty acids in stools were unchanged.
摘要：
便秘在儿童中很常见，可以显着影响生活质量。据报道，益生元对成人便秘有帮助，但是很少有研究检查它们在幼儿中的使用。在这项研究中,1-kestose（kestose）的作用，具有优异的双歧杆菌生长特性，在一个随机的幼儿园儿童便秘（n=11）与麦芽糖（n=12）进行了比较，双盲研究.每天三克红藻糖持续8周不影响粪便特性，但每周排便次数显著增加(中位数；3→4次/周，p=0.017，效应大小=0.53）。肠杆菌显著减少，双歧杆菌增加的趋势，并观察到一种趋势减少的梭状芽胞杆菌严格的摄食后，而粪便中短链脂肪酸的浓度没有变化。
