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Abstract：
Sarcoidosis is a multisystem granulomatous disease of unknown origin. The most frequent localizations are thoracic lymph nodes and/or parenchymal lung disease, nevertheless any other organ may be involved. Musculoskeletal sarcoidosis, previously considered a rare manifestation of the disease, is presently recognized with increasing frequency, due to the development of modern imaging modalities. The classical X-ray sign of bone sarcoidosis is the image of lace in the phalanges of the hands. Most other locations present with atypical radiological images. Therefore, they may mimic metastatic neoplastic disease, especially when they are the first sign of sarcoidosis not previously recognized. On such occasions, none of the imaging methods will give the correct diagnosis, histopathological verification, monitoring of lesions or clinical data in a patient with confirmed sarcoidosis are indicated. The article summarizes the current status of knowledge concerning the recognition and therapy of bone sarcoidosis. In addition, an illustrative case of patient with bone and bone marrow sarcoidosis is presented.
摘要：
结节病是一种不明原因的多系统肉芽肿性疾病。最常见的定位是胸部淋巴结和/或肺实质疾病，然而，任何其他器官都可能参与其中。肌肉骨骼结节病，以前被认为是这种疾病的罕见表现，目前认识到频率越来越高，由于现代成像模式的发展。骨结节病的经典X射线征象是手指骨中的花边图像。大多数其他位置存在非典型放射学图像。因此,它们可能模仿转移性肿瘤疾病，特别是当它们是结节病的第一个迹象之前没有认识到。在这种场合,没有一种成像方法能给出正确的诊断，组织病理学验证,对结节病确诊患者的病变或临床数据进行监测。本文总结了有关骨结节病的认识和治疗的知识现状。此外,介绍了一例骨和骨髓结节病患者的说明性病例。
