PDF(Pubmed)
Abstract：
(1) Background: The recurrence rate of childhood recurrent sinusitis varies widely between 12% and 50%, with the postoperative recurrence risk factors remaining largely unidentified. We sought to enhance the understanding of chronic rhinosinusitis (CRS) via a retrospective observational childhood cohort. (2) Methods: The study recruited 125 cases. Demographic data and univariate and multivariate logistic regression analyses were conducted to investigate potential risk factors of childhood recurrent sinusitis following functional endoscopic sinus surgery (FESS). (3) Results: A postoperative recurrence rate of 21.6% was determined. Among the participants, 21 cases presented a history of allergic rhinitis (AR), with the remaining 104 cases being AR-free. A significantly heightened recurrence rate was noted in those bearing a history of AR compared to their counterparts devoid of such history (p < 0.000). The fully adjusted logistic regression model indicated a 21.04-fold increased risk of postoperative recurrence in childhood CRS bearing a history of AR compared to those without an AR history (p = 0.000), highlighting the history of AR as an independent risk factor for postoperative childhood recurrent sinusitis (p = 0.001); (4) Conclusions: The data implicate AR as an independent risk factor for postoperative childhood recurrent sinusitis.
摘要：
（1）背景：儿童复发性鼻窦炎的复发率在12％至50％之间差异很大，术后复发的危险因素仍未明确。我们试图通过回顾性观察儿童队列来增强对慢性鼻-鼻窦炎（CRS）的理解。(2)方法:本研究纳入125例。进行了人口统计学数据以及单变量和多变量逻辑回归分析，以调查功能性内窥镜鼻窦手术（FESS）后儿童复发性鼻窦炎的潜在危险因素。（3）结果：术后复发率为21.6％。在参与者中，21例有变应性鼻炎（AR）病史，其余104例无AR。与没有AR病史的患者相比，有AR病史的患者的复发率显着升高（p<0.000）。完全调整的逻辑回归模型表明，与没有AR病史的儿童CRS相比，有AR病史的儿童CRS术后复发风险增加了21.04倍（p=0.000）。强调AR病史是术后儿童复发性鼻窦炎的独立危险因素（p=0.001）；（4）结论：数据提示AR是术后儿童复发性鼻窦炎的独立危险因素。
