关键词: drug discovery flow chemistry marine drugs novel technologies photochemistry

Mesh : Drug Discovery Technology Chemistry, Pharmaceutical

来  源:   DOI:10.3390/md21070402   PDF(Pubmed)

Abstract:
In this perspective, we showcase the benefits of continuous flow chemistry and photochemistry and how these valuable tools have contributed to the synthesis of organic scaffolds from the marine environment. These technologies have not only facilitated previously described synthetic pathways, but also opened new opportunities in the preparation of novel organic molecules with remarkable pharmacological properties which can be used in drug discovery programs.
摘要:
从这个角度来看,我们展示了连续流化学和光化学的好处,以及这些有价值的工具如何从海洋环境中合成有机支架。这些技术不仅促进了先前描述的合成途径,而且在制备具有显着的药理特性的新型有机分子方面也开辟了新的机会,可用于药物发现计划。
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