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Abstract：
BACKGROUND: Muco-epidermoid carcinomas are primarily the subtypes of salivary gland tumors that can rarely originate within the respiratory tract. Our case highlights the occurrence of an unusual, localized, endo-bronchial muco-epidermoid cancer. We aim to strengthen the evidence of occurrence of this distinct variety of lung cancer in our country as little is known about this rare subclass of lung cancer.
METHODS: We report a case of a 22-year-old female patient, belonging to Karachi, Pakistan, who presented with respiratory symptoms and upon work-up, was diagnosed with a low-grade, localized muco-epidermoid carcinoma of the lung. She underwent surgical resection successfully and was advised to get evaluated for adjuvant radiotherapy.
UNASSIGNED: Localized low-grade MEC respond well to surgical resection in contrast to high-grade MEC which is associated with poor prognosis thus requiring adjuvant radiotherapy to improve survival outcomes.
CONCLUSIONS: Lung cancers can be unusually of muco-epidermoid origin. It has been uncommonly found in the world including Pakistan. Special attention with validated data is therefore needed, for developing guidelines for the optimal management of such neoplasms.
METHODS: We report a case of a 22-year-old female patient, belonging to Karachi, Pakistan, who presented with respiratory symptoms and upon work-up, was diagnosed with a low-grade, localized muco-epidermoid carcinoma of the lung. She underwent surgical resection successfully and was advised to get evaluated for adjuvant radiotherapy.
UNASSIGNED: Localized low-grade MEC respond well to surgical resection in contrast to high-grade MEC which is associated with poor prognosis thus requiring adjuvant radiotherapy to improve survival outcomes.
CONCLUSIONS: Lung cancers can be unusually of muco-epidermoid origin. It has been uncommonly found in the world including Pakistan. Special attention with validated data is therefore needed, for developing guidelines for the optimal management of such neoplasms.
摘要：
背景：表皮样癌主要是唾液腺肿瘤的亚型，很少起源于呼吸道。我们的案例强调了一种不寻常的事情的发生，局部化,支气管粘膜表皮样癌。我们的目标是加强在我国发生这种不同种类的肺癌的证据，因为对这种罕见的肺癌亚类知之甚少。
方法：我们报告一例22岁女性患者，属于卡拉奇,巴基斯坦,出现呼吸道症状和检查时，被诊断为低年级，肺局部粘液表皮样癌。她成功接受了手术切除，并建议接受辅助放疗评估。
■局部低级别MEC对手术切除反应良好，而高级别MEC与不良预后相关，因此需要辅助放疗以改善生存结果。
结论：肺癌可以是异常的粘液表皮样起源。这在包括巴基斯坦在内的世界上是罕见的。因此，需要特别注意经过验证的数据，制定此类肿瘤最佳管理指南。
方法：我们报告一例22岁女性患者，属于卡拉奇,巴基斯坦,出现呼吸道症状和检查时，被诊断为低年级，肺局部粘液表皮样癌。她成功接受了手术切除，并建议接受辅助放疗评估。
■局部低级别MEC对手术切除反应良好，而高级别MEC与不良预后相关，因此需要辅助放疗以改善生存结果。
结论：肺癌可以是异常的粘液表皮样起源。这在包括巴基斯坦在内的世界上是罕见的。因此，需要特别注意经过验证的数据，制定此类肿瘤最佳管理指南。
