PDF(Pubmed)
Abstract：
Berries are rich in (poly)phenols, and these compounds may be beneficial to human health. Estimating berry consumption through self-reported questionnaires has been challenging due to compliance issues and a lack of precision. Estimation via food-derived biomarkers in biofluids was proposed as a complementary alternative. We aimed to review and update the existing evidence on biomarkers of intake for six different types of berries. A systematic literature search was performed to update a previous systematic review on PubMed, Web of Science, and Scopus from January 2020 until December 2022. Out of 42 papers, only 18 studies were eligible. A multimetabolite panel is suggested for blueberry and cranberry intake. Proposed biomarkers for blueberries include hippuric acid and malvidin glycosides. For cranberries, suggested biomarkers are glycosides of peonidin and cyanidin together with sulfate and glucuronide conjugates of phenyl-γ-valerolactone derivatives. No new metabolite candidates have been found for raspberries, strawberries, blackcurrants, and blackberries. Further studies are encouraged to validate these multimetabolite panels for improving the estimation of berry consumption.
摘要：
浆果富含（聚）酚，这些化合物可能对人体健康有益。由于合规性问题和缺乏准确性，通过自我报告问卷估算浆果消费量一直具有挑战性。通过生物流体中食物来源的生物标志物进行估算被提议作为补充替代方案。我们旨在回顾和更新关于六种不同类型浆果摄入量的生物标志物的现有证据。进行了系统的文献检索，以更新以前对PubMed的系统评价，WebofScience,和Scopus从2020年1月到2022年12月。在42份论文中，只有18项研究符合资格.建议使用多代谢物面板摄入蓝莓和蔓越莓。蓝莓的拟议生物标志物包括马尿酸和malvidin糖苷。对于小红莓，建议的生物标志物是牡丹苷和花青素的糖苷以及苯基-γ-戊内酯衍生物的硫酸盐和葡糖苷酸缀合物。没有发现覆盆子的新代谢物候选物，草莓,黑醋栗,还有黑莓.鼓励进一步的研究来验证这些多代谢物面板，以改善对浆果消费量的估计。
