Abstract:
Folliculosebaceous cystic hamartoma is a cutaneous malformation composed of a cystic folliculosebaceous structure associated with mesenchymal elements, generally consisting of fibrous stroma, adipocytes and small vascular channels. We report the case of a 55-year-old female patient with a cutaneous nodule of the right nasal wing. Microscopically, the lesion showed a dilated hair follicle with multiple sebaceous glands, surrounded by a mesenchymal component composed of fibromyxoid stroma, spindle cells, mature-appearing adipocytes and collagen bundles, resembling spindle cell lipoma, associated with an additional neural component, consisting of small nerve bundles. In folliculosebaceous cystic hamartoma, the association of spindle cell lipomatous and neural components has not previously reported.
摘要:
毛囊皮脂腺囊性错构瘤是由与间充质成分相关的囊性毛囊皮脂腺结构组成的皮肤畸形,通常由纤维基质组成,脂肪细胞和小血管通道。我们报告了一名55岁的女性患者,其右鼻翼皮肤结节。微观上,病变显示毛囊扩张,有多个皮脂腺,由纤维粘液样基质组成的间充质成分包围,梭形细胞,成熟的脂肪细胞和胶原蛋白束,类似梭形细胞脂肪瘤,与额外的神经成分有关,由小神经束组成。在毛囊皮脂腺囊性错构瘤中,梭形细胞脂肪瘤和神经成分的关联以前没有报道。