关键词: Chronic kidney disease Continuous ambulatory peritoneal dialysis Paracoccidioides spp. Peritonitis

Mesh : Humans Male Middle Aged Peritoneal Dialysis, Continuous Ambulatory / adverse effects Paracoccidioides Peritonitis / diagnosis microbiology Ascitic Fluid / microbiology Kidney Failure, Chronic / complications therapy Brazil

来  源:   DOI:10.1016/j.bjid.2023.102792   PDF(Pubmed)

Abstract:
Paracoccidioidomycosis is a systemic mycosis found mainly in South America and is the most prevalent endemic and systemic mycosis in Brazil. The purpose of this paper was to report the case of a male patient who developed peritonitis caused by Paracoccidioides spp. Forty-eight-year-old, male patient, with type I Diabetes mellitus and chronic kidney disease who was undergoing a Continuous Ambulatory Peritoneal Dialysis (CAPD) program. After eighteen months of peritoneal dialysis, the patient developed turbidity of the peritoneal fluid and was diagnosed with peritonitis. Direct mycological examination of the peritoneal fluid revealed yeasts with morphology suggestive of Paracoccidioides spp. The patient was treated with sulfamethoxazole-trimethoprim (1,600 mg/320 mg dose/day) for 61 days, but he died because a bacterial septic shock. The diagnosis of opportunistic PCM peritonitis was later confirmed by autopsy and Paracoccidioides spp. isolation. This is the first reported case of a patient on CAPD who experienced complications due peritonitis caused by opportunistic PCM.
摘要:
副孢子菌病是主要在南美发现的全身性真菌病,是巴西最普遍的地方性和全身性真菌病。本文的目的是报告一名男性患者,该患者由副病菌引起的腹膜炎。四十八岁,男性患者,患有I型糖尿病和慢性肾脏疾病的患者正在接受连续非卧床腹膜透析(CAPD)计划。腹膜透析18个月后,患者出现腹膜液浑浊,并被诊断为腹膜炎。直接对腹膜液进行真菌学检查,发现酵母的形态提示副病菌。患者接受磺胺甲恶唑-甲氧苄啶(1,600mg/320mg剂量/天)治疗61天,但他死于细菌性脓毒性休克.后来通过尸检和副球菌属证实了机会性PCM腹膜炎的诊断。隔离。这是首次报道的CAPD患者因机会性PCM引起的腹膜炎而出现并发症。
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