PDF(Pubmed)
Abstract：
Food borne pathogens are one of the most common yet concerning cause of illnesses around the globe. These microbes invade the body via food items, through numerous mediums of contamination and it is impossible to completely eradicate these organisms from food. Extensive research has been made regarding their treatment. Unfortunately, the only available treatment currently is by antibiotics. Recent exponential increase in antibiotic resistance and the side effect of synthetic compounds have established a need for alternate therapies that could be utilized either on their own or along with antibiotics to provide protection against food-borne diseases. The aim of this review is to provide information regarding some common food borne diseases, their current and possible natural treatment. It will include details regarding some common foodborne pathogens, the disease they cause, prevalence, manifestations and treatment of the respective disease. Some natural modes of potential treatment will be summarized, which including phytochemicals, derived from plants either as crude extracts or as purified form and Bacteriocins as microbial based treatment, obtained from various types of bacteria. The paper will describe their mechanism of action, classification, susceptible organisms, some antimicrobial compounds and producing organisms, application in food systems and as potential treatment. Along with that, synthetic treatment i.e., antibiotics will be discussed including the first-line treatment of some common food borne infections, prevalence and mechanism of resistance against antibiotics in the pathogens.
摘要：
食源性病原体是全球最常见但最重要的疾病原因之一。这些微生物通过食物侵入人体，通过众多的污染介质，不可能从食物中完全根除这些生物。已经对他们的治疗进行了广泛的研究。不幸的是,目前唯一可用的治疗方法是抗生素。最近抗生素抗性的指数增加和合成化合物的副作用已经建立了对可以单独使用或与抗生素一起使用以提供针对食源性疾病的保护的替代疗法的需求。这篇综述的目的是提供有关一些常见食源性疾病的信息，他们目前和可能的自然疗法。它将包括一些常见的食源性病原体的细节，它们引起的疾病，患病率,相应疾病的表现和治疗。将总结一些潜在治疗的自然模式，包括植物化学物质，来自植物的粗提物或纯化形式和细菌素作为微生物处理，从各种类型的细菌中获得。本文将描述它们的作用机制，分类，易感生物，一些抗菌化合物和产生生物体，在食品系统中的应用和作为潜在的治疗方法。除此之外，合成处理，即，将讨论抗生素，包括一些常见食源性感染的一线治疗，病原菌对抗生素的耐药率和耐药机制。
