Abstract:
Neuroendocrine tumors (NETs) up to 80% may have metastatic disease to lymph nodes, liver, and bones upon diagnosis due to their indolent course and benign nature. However, metastasis to the breast from gastropancreatic-neuroendocrine tumors (GEP-NETs) is unusual and rarely reported. Furthermore, such metastases may mimic a primary breast carcinoma clinically and radiologically. This case report illustrates an unusual presentation of metastasis to the right breast in addition to liver, pancreas, and lymph nodal metastases in a patient with ileal NET who was operated upon 5 years back. The metastases were detected by somatostatin receptor-based imaging and post-therapy scan which was confirmed by cytology and immunocytochemistry.
摘要:
神经内分泌肿瘤(NETs)高达80%可能有淋巴结转移疾病,肝脏,和骨骼在诊断时由于其惰性和良性性质。然而,胃胰腺-神经内分泌肿瘤(GEP-NETs)向乳腺的转移并不常见,也很少报道.此外,这种转移可能在临床和放射学上模仿原发性乳腺癌。此病例报告显示,除肝脏外,右乳转移的异常表现,胰腺,回肠NET患者的淋巴结转移,该患者在5年前接受手术。通过基于生长抑素受体的成像和治疗后扫描检测转移,并通过细胞学和免疫细胞化学证实。