Abstract：
OBJECTIVE: To explore the diagnosis and treatment of ectopic seminal duct opening into the urethra.
METHODS: We reviewed the literature and retrospectively analyzed the clinical data on a case of sex development abnormality. The patient was a 16-year-old gender female seeking medical improvement of female signs, admitted to hospital with \"clitoris hypertrophy, no menstruation and chromosome karyotype 46XY\", treated by bilateral orchiectomy, and simultaneously examined by seminal vesiculography and cystoscopy.
RESULTS: Seminal vesiculography showed the ectopic opening of the right ejaculatory duct into the urethra accompanied by dysplasia of the seminal vesicle. Cystoscopy exhibited a fissrure-like opening in the right wall of the urethra but no verumontanum. Postoperative pathology revealed bilateral undeveloped testes and epididymides.
CONCLUSIONS: Ectopic opening of the seminal duct into the urethra is extremely rare and often complicated by many malformations, for the diagnosis of which the most reliable options are seminal vesiculography and retrograde radiography through the ectopic orifice under the cystoscope. The treatment of the disease should follow the principles of timeliness, individualization and consideration of associated malformations.
METHODS: We reviewed the literature and retrospectively analyzed the clinical data on a case of sex development abnormality. The patient was a 16-year-old gender female seeking medical improvement of female signs, admitted to hospital with \"clitoris hypertrophy, no menstruation and chromosome karyotype 46XY\", treated by bilateral orchiectomy, and simultaneously examined by seminal vesiculography and cystoscopy.
RESULTS: Seminal vesiculography showed the ectopic opening of the right ejaculatory duct into the urethra accompanied by dysplasia of the seminal vesicle. Cystoscopy exhibited a fissrure-like opening in the right wall of the urethra but no verumontanum. Postoperative pathology revealed bilateral undeveloped testes and epididymides.
CONCLUSIONS: Ectopic opening of the seminal duct into the urethra is extremely rare and often complicated by many malformations, for the diagnosis of which the most reliable options are seminal vesiculography and retrograde radiography through the ectopic orifice under the cystoscope. The treatment of the disease should follow the principles of timeliness, individualization and consideration of associated malformations.
摘要：
目的：探讨尿道异位的诊断和治疗。
方法：我们复习文献，回顾性分析一例性发育异常的临床资料。患者是一名16岁的性别女性，寻求女性体征的医疗改善，因阴蒂肥大入院，无月经和染色体核型46XY\“，通过双侧睾丸切除术治疗，同时进行精囊造影和膀胱镜检查。
结果：精囊造影显示右侧射精管异位通向尿道，伴有精囊发育不良。膀胱镜检查在尿道右壁显示出像fissrure一样的开口，但没有Verumontanum。术后病理显示双侧睾丸和附睾不发达。
结论：精管异位通向尿道是极为罕见的，并且经常并发许多畸形，对于诊断，最可靠的选择是精囊造影和膀胱镜下异位孔逆行造影。本病的治疗应遵循时效性原则,个性化和相关畸形的考虑。
方法：我们复习文献，回顾性分析一例性发育异常的临床资料。患者是一名16岁的性别女性，寻求女性体征的医疗改善，因阴蒂肥大入院，无月经和染色体核型46XY\“，通过双侧睾丸切除术治疗，同时进行精囊造影和膀胱镜检查。
结果：精囊造影显示右侧射精管异位通向尿道，伴有精囊发育不良。膀胱镜检查在尿道右壁显示出像fissrure一样的开口，但没有Verumontanum。术后病理显示双侧睾丸和附睾不发达。
结论：精管异位通向尿道是极为罕见的，并且经常并发许多畸形，对于诊断，最可靠的选择是精囊造影和膀胱镜下异位孔逆行造影。本病的治疗应遵循时效性原则,个性化和相关畸形的考虑。
