PDF(Pubmed)
Abstract：
Contrast enhanced ultrasound (CEUS) has been widely implemented in clinical practice because of the enormous quantity of information it provides, along with its low cost, reproducibility, minimal invasiveness, and safety of the second-generation ultrasound contrast agents. To overcome the limitation of CEUS given by the subjective evaluation of the contrast enhancement behaviour, quantitative analysis of contrast kinetics with generation of time-intensity curves has been introduced in recent years. The quantification of perfusion parameters [named as dynamic-CEUS (D-CEUS)] has several applications in gastrointestinal neoplastic and inflammatory disorders. However, the limited availability of large studies and the heterogeneity of the technologies employed have precluded the standardisation of D-CEUS, which potentially represents a valuable tool for clinical practice in management of gastrointestinal diseases. In this article, we reviewed the evidence exploring the application of D-CEUS in gastrointestinal diseases, with a special focus on liver, pancreas, and inflammatory bowel diseases.
摘要：
超声造影(CEUS)因其提供的大量信息而在临床上得到了广泛的应用,加上它的低成本，再现性，最小的侵入性，第二代超声造影剂的安全性。为了克服由对比增强行为的主观评价给出的CEUS的局限性,近年来，已经引入了生成时间强度曲线的对比动力学定量分析。灌注参数的定量[称为动态CEUS（D-CEUS）]在胃肠道肿瘤和炎症性疾病中具有多种应用。然而,大型研究的有限可用性和所采用技术的异质性阻碍了D-CEUS的标准化，这可能代表了一个有价值的工具，用于临床实践中的胃肠道疾病的管理。在这篇文章中,我们回顾了探索D-CEUS在胃肠道疾病中应用的证据，特别关注肝脏，胰腺,和炎症性肠病。
