关键词: Chemotherapy gestational choriocarcinoma hydatidiform mole metastasis

Mesh : Pregnancy Female Humans Adult Uterine Neoplasms / diagnosis pathology Choriocarcinoma / diagnosis drug therapy pathology Uterus / pathology Hydatidiform Mole / complications diagnosis pathology Kidney Neoplasms / diagnosis complications Kidney / pathology

来  源:   DOI:10.4103/jcrt.jcrt_1880_20

Abstract:
Gestational choriocarcinomas are malignant neoplasms generally arising in the uterus in women of childbearing age. These are aggressive tumors with a high incidence of metastasis to vascular organs such as the lung, liver, and brain. Renal metastasis is extremely rare with low incidence rate and very few cases have been reported in literature. Hereby, we report a rare case of metastatic choriocarcinoma to the kidney in a 29-year-old female 10 years after resection of a hydatidiform mole. The histopathological diagnosis was made on a nephrectomy specimen. Pelvic and abdominal scan did not show any abnormal radiological findings. She was started on first-line chemotherapy and showed a complete response. In conclusion, gestational or primary nongestational choriocarcinomas should always be considered as a differential diagnosis in young females of reproductive age group presenting with flank abdominal pain, unexplained hematuria, and atypical renal tumor histology.
摘要:
妊娠绒毛膜癌是育龄妇女子宫内常见的恶性肿瘤。这些是侵袭性肿瘤,转移到血管器官如肺的发生率很高,肝脏,和大脑。肾转移极为罕见,发生率低,文献报道很少。特此,我们报道了一例罕见的29岁女性肾转移性绒毛膜癌病例,10年后切除葡萄胎。组织病理学诊断是在肾切除术标本上进行的。盆腔和腹部扫描未显示任何异常的放射学发现。她开始接受一线化疗,并表现出完全反应。总之,妊娠性或原发性非妊娠性脉络膜癌应始终被视为育龄组年轻女性的鉴别诊断,表现为侧腹疼痛,不明原因的血尿,和不典型的肾肿瘤组织学。
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