PDF(Pubmed)
Abstract：
Granular parakeratosis (GP) is a unique keratotic disorder that often affects the intertriginous areas. GP usually presents as erythematous or brownish hyperkeratotic papules or plaques and can be further classified into five types. GP of the eccrine ostium is a rare subtype; its pathological defects are mainly localized to the stratum corneum of the eccrine ostia. Due to its rarity, there is usually a delay in diagnosing GP, and these patients are often misdiagnosed with other dermatological conditions. In this report, we present the case of a 64-year-old Thai female who presented with recurrent pruritic erythematous rashes on her neck since approximately 40 years. She was previously diagnosed with eczema or folliculitis. Histopathological examination confirmed a final diagnosis of GP of the eccrine ostium. She was advised to avoid excessive heat and keep her intertriginous areas dry. Her condition improved significantly during the follow-up visit.
摘要：
颗粒性角化不全（GP）是一种独特的角化疾病，通常会影响三层体间区域。GP通常表现为红斑或褐色角化过度丘疹或斑块，可进一步分为五种类型。内分泌口的GP是一种罕见的亚型；其病理缺陷主要局限于内分泌口的角质层。由于它的稀有性,诊断GP通常会有延迟，这些患者经常被误诊为其他皮肤病。在这份报告中,我们介绍了1例64岁的泰国女性,她的颈部出现复发性瘙痒性红斑性皮疹,大约40年后.她以前被诊断为湿疹或毛囊炎。组织病理学检查证实了内分泌口GP的最终诊断。建议她避免过热，并保持杂物区域干燥。在随访期间，她的病情明显改善。
