关键词: clinical outcomes consensus research contextual factors nominal group technique placebo

来  源:   DOI:10.3389/fpsyg.2023.1178560   PDF(Pubmed)

Abstract:
UNASSIGNED: Emerging literature suggests contextual factors are important components of therapeutic encounters and may substantially influence clinical outcomes of a treatment intervention. At present, a single consensus definition of contextual factors, which is universal across all health-related conditions is lacking. The objective of this study was to create a consensus definition of contextual factors to better refine this concept for clinicians and researchers.
UNASSIGNED: The study used a multi-stage virtual Nominal Group Technique (vNGT) to create and rank contextual factor definitions. Nominal group techniques are a form of consensus-based research, and are beneficial for identifying problems, exploring solutions and establishing priorities.
UNASSIGNED: International.
UNASSIGNED: The initial stages of the vNGT resulted in the creation of 14 independent contextual factor definitions. After a prolonged discussion period, the initial definitions were heavily modified, and 12 final definitions were rank ordered by the vNGT participants from first to last.
UNASSIGNED: The 10 international vNGT participants had a variety of clinical backgrounds and research specializations and were all specialists in contextual factors research.
UNASSIGNED: A sixth round was used to identify a final consensus, which reflected the complexity of contextual factors and included three primary domains: (1) an overall definition; (2) qualifiers that serve as examples of the key areas of the definition; and (3) how contextual factors may influence clinical outcomes.
UNASSIGNED: Our consensus definition of contextual factors seeks to improve the understanding and communication between clinicians and researchers. These are especially important in recognizing their potential role in moderating and/or mediating clinical outcomes.
摘要:
新兴文献表明,背景因素是治疗性接触的重要组成部分,并且可能会严重影响治疗干预的临床结果。目前,上下文因素的单一共识定义,缺乏所有与健康相关的疾病的普遍性。这项研究的目的是创建一个一致的定义的背景因素,以更好地完善这一概念,为临床医生和研究人员。
该研究使用了多阶段虚拟标称组技术(vNGT)来创建和排名上下文因素定义。名义分组技术是一种基于共识的研究形式,有利于发现问题,探索解决方案并确定优先事项。
国际。
vNGT的初始阶段导致创建了14个独立的上下文因素定义。经过长时间的讨论,最初的定义被大量修改,12个最终定义由vNGT参与者从第一到最后排序。
10名国际vNGT参与者具有各种临床背景和研究专长,并且都是上下文因素研究的专家。
第六轮被用来确定最终共识,这反映了背景因素的复杂性,包括三个主要领域:(1)总体定义;(2)作为定义关键领域示例的限定词;(3)背景因素如何影响临床结局.
我们对上下文因素的共识定义旨在改善临床医生和研究人员之间的理解和沟通。这些对于认识到它们在调节和/或介导临床结果中的潜在作用尤其重要。
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