PDF(Pubmed)
Abstract：
Flaxseed (Linum usitatissimum L) is an ancient perennial plant species regarded as a multipurpose plant owing to its richness in omega-3 polyunsaturated fatty acids (PUFA) including α-linolenic acid (ALA). The extensive biochemical analysis of flaxseed resulted in the identification of its bioactive, i.e., lignans with potential application in the improvement of human health. Flaxseed oil, fibers, and lignans exert potential health benefits including reduction of cardiovascular disease, atherosclerosis, diabetes, cancer, arthritis, osteoporosis, and autoimmune and neurological disorders that have led to the diversification of flaxseed plant applications. This comprehensive review focuses on flaxseed oil as the major product of flaxseed with emphasis on the interrelationship between its chemical composition and biological effects. Effects reviewed include antioxidant, anti-inflammatory, antimicrobial, anticancer, antiulcer, anti-osteoporotic, cardioprotective, metabolic, and neuroprotective. This study provides an overview of flaxseed oil effects with the reported action mechanisms related to its phytochemical composition and in comparison, to other PUFA-rich oils. This study presents the most updated and comprehensive review summarizing flaxseed oil\'s health benefits for the treatment of various diseases.
摘要：
亚麻籽（LinumusitatissimumL）是一种古老的多年生植物物种，由于其丰富的omega-3多不饱和脂肪酸（PUFA）包括α-亚麻酸（ALA）而被认为是多用途植物。广泛的生物化学分析的亚麻籽导致鉴定其生物活性，即，木脂素在改善人类健康方面具有潜在的应用价值。亚麻籽油,纤维，和木脂素发挥潜在的健康益处，包括减少心血管疾病，动脉粥样硬化,糖尿病,癌症,关节炎,骨质疏松,以及导致亚麻籽植物应用多样化的自身免疫性和神经系统疾病。这篇综合综述侧重于亚麻籽油作为亚麻籽的主要产品，重点是其化学成分与生物效应之间的相互关系。审查的效果包括抗氧化剂，抗炎,抗菌，抗癌，抗溃疡,抗骨质疏松，心脏保护,新陈代谢，和神经保护。本研究概述了亚麻籽油的影响，并报道了与其植物化学成分相关的作用机制，其他富含PUFA的油。本研究提供了最新和全面的综述，总结了亚麻籽油对治疗各种疾病的健康益处。
