关键词: cytoflavin ethylmethylhydroxypyridine succinate humic acids performance capability stress

来  源:   DOI:10.1007/s10517-023-05836-9

Abstract:
The effect of humic acids and substances with similar action - derivatives of succinic acid (ethylmethylhydroxypyridine succinate) and combined agent consisting of succinic acid, nicotinamide, riboflavin, and riboxin on the performance and stress resistance of experimental rats was studied. Performance was assessed in the test of exhaustive forced swimming with a load, stress resistance was evaluated by the serum level of corticosterone and open field behavior, and the state of anaerobic metabolism was estimated by the serum level of lactate after swimming test. Humic acids from peat showed anti-stress activity comparable to that of the officinal preparation and preventive effect on fatigue during physical exercise. They can be recommended as a component for the development of drugs that increase human performance and stress resistance.
摘要:
腐殖酸和具有类似作用的物质的作用-琥珀酸衍生物(乙基甲基羟基吡啶琥珀酸酯)和由琥珀酸组成的组合剂,烟酰胺,核黄素,研究了利波辛对实验大鼠的性能和抗应激能力。在带负荷的力竭强迫游泳测试中评估了性能,通过血清皮质酮水平和开放场行为来评估应激抗性,通过游泳试验后的血清乳酸水平来评估无氧代谢状态。泥炭中的腐殖酸具有与药用制剂相当的抗应激活性,并且对体育锻炼中的疲劳具有预防作用。可以推荐它们作为开发增加人类表现和抗压力的药物的组成部分。
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