Abstract:
A woman in her 20s presented to our clinic with a lower gastrointestinal infection. When we administered intravenous antibacterial and vitamin infusions, she developed anaphylaxis. We performed skin tests to investigate the cause, and an intradermal test was positive for a 1% intravenous vitamin complex. We then performed a component-specific test, which was positive for thiamine disulfide phosphate, a vitamin B1 derivative. We therefore diagnosed anaphylaxis due to thiamine disulfide phosphate. No previous reports have described cross-reactivity between vitamin B1 derivatives. In our case, however, the patient tested positive for fluthiamine hydrochloride, suggesting cross-reactivity. Intravenous vitamin complexes are used in daily clinical practice and should be administered with caution because of the possibility of anaphylaxis, although it occurs infrequently.
摘要:
一名20多岁的妇女因胃肠道感染而来到我们的诊所。当我们静脉注射抗菌药物和维生素输注时,她出现了过敏反应.我们做了皮肤测试来调查原因,1%静脉注射维生素复合物的皮内试验呈阳性。然后,我们执行了特定于组件的测试,硫胺素二硫化物磷酸盐呈阳性,维生素B1衍生物。因此,我们诊断为由硫胺素二硫化物磷酸盐引起的过敏反应。以前没有报道描述维生素B1衍生物之间的交叉反应性。在我们的案例中,然而,该患者的盐酸氟硫胺素检测呈阳性,提示交叉反应性。静脉内维生素复合物用于日常临床实践,应谨慎使用,因为有可能发生过敏反应,虽然它很少发生。