PDF(Pubmed)
Abstract：
BACKGROUND: Uterine myomas represent the most frequently diagnosed tumors among women of childbearing age. Symptoms often include profuse menstrual bleeding, diminished quality of life, and in some cases, infertility. The size and position of the fibroids typically influence the condition\'s manifestations. Moreover, symptomatology often varies depending on the fibroids\' location. This investigation aimed to discern if there exists a significant correlation between life quality, reoccurrence rate, quality of life, and recurrence levels among patients who have undergone myomectomy and uterine fibroid embolization, respectively.
METHODS: A retrospective cross-sectional study was conducted to compare the rates of recurrence and impacts on life quality between uterine fibroid embolization and myomectomy in women diagnosed with uterine myomas. Data were collected from 152 women who sought treatment at the Obstetrics and Gynecology clinic and also the Interventional Radiology clinic between January 2009 and January 2021. Thirteen participants were excluded due to the inability to maintain contact. The trial encompassed 76 patients who underwent myomectomy and 63 who had uterine fibroid embolization. In both groups, the life quality of 50 patients, five years postsurgery, was assessed using the UFS-QOL measure. Eligible participants were females between 20 and 40 years, with symptomatic Type 3-5 fibroids as per the FIGO classification, and with no comorbidities. Individuals under 20 or over 40 years, or those with fibroids classified as FIGO types 1,2,6,7,8, were not included. Other exclusion criteria included pregnancy status, abnormal endometrial biopsy results, abnormal smear tests, polyps, cancer, adenomyosis and coagulation disorders.
RESULTS: The recurrence of fibroids was identified through symptomatology and diagnostic radiological methods. The recurrence rate was found to be 31.6% (n=24) for myomectomy patients and 14.3% (n=9) for those who underwent uterine fibroid embolization, with no statistically significant difference between the two groups (p > 0.05). The group subjected to myomectomy exhibited fewer symptoms, lower anxiety, and better physical mood scores. The myomectomy group displayed higher average anxiety scores (p<0.01). There were no significant disparities in control, consciousness, sexual function, or overall scores between the two groups. Symptoms and anxiety saw a marked reduction in the first postoperative year compared to the preoperative period (p<0.01). Compared to presurgery, energy, mood, awareness, and sexual function exhibited significant improvements in the first and fifth postoperative years (p<0.01).
CONCLUSIONS: Our findings suggest a nonsignificant recurrence rate in the myomectomy group compared to the uterine artery embolization group. Notably, the decrease in symptom occurrence and anxiety following myomectomy was significantly favorable in terms of quality of life. While embolization was offered as a therapeutic option, myomectomy yielded more favorable results concerning quality of life.
METHODS: A retrospective cross-sectional study was conducted to compare the rates of recurrence and impacts on life quality between uterine fibroid embolization and myomectomy in women diagnosed with uterine myomas. Data were collected from 152 women who sought treatment at the Obstetrics and Gynecology clinic and also the Interventional Radiology clinic between January 2009 and January 2021. Thirteen participants were excluded due to the inability to maintain contact. The trial encompassed 76 patients who underwent myomectomy and 63 who had uterine fibroid embolization. In both groups, the life quality of 50 patients, five years postsurgery, was assessed using the UFS-QOL measure. Eligible participants were females between 20 and 40 years, with symptomatic Type 3-5 fibroids as per the FIGO classification, and with no comorbidities. Individuals under 20 or over 40 years, or those with fibroids classified as FIGO types 1,2,6,7,8, were not included. Other exclusion criteria included pregnancy status, abnormal endometrial biopsy results, abnormal smear tests, polyps, cancer, adenomyosis and coagulation disorders.
RESULTS: The recurrence of fibroids was identified through symptomatology and diagnostic radiological methods. The recurrence rate was found to be 31.6% (n=24) for myomectomy patients and 14.3% (n=9) for those who underwent uterine fibroid embolization, with no statistically significant difference between the two groups (p > 0.05). The group subjected to myomectomy exhibited fewer symptoms, lower anxiety, and better physical mood scores. The myomectomy group displayed higher average anxiety scores (p<0.01). There were no significant disparities in control, consciousness, sexual function, or overall scores between the two groups. Symptoms and anxiety saw a marked reduction in the first postoperative year compared to the preoperative period (p<0.01). Compared to presurgery, energy, mood, awareness, and sexual function exhibited significant improvements in the first and fifth postoperative years (p<0.01).
CONCLUSIONS: Our findings suggest a nonsignificant recurrence rate in the myomectomy group compared to the uterine artery embolization group. Notably, the decrease in symptom occurrence and anxiety following myomectomy was significantly favorable in terms of quality of life. While embolization was offered as a therapeutic option, myomectomy yielded more favorable results concerning quality of life.
摘要：
背景：子宫肌瘤是育龄妇女中最常诊断的肿瘤。症状通常包括大量月经出血，生活质量下降，在某些情况下,不孕症。肌瘤的大小和位置通常会影响病情的表现。此外，症状学通常因肌瘤的位置而异。这项调查旨在辨别生活质量之间是否存在显著的相关性，复发率,生活质量,子宫肌瘤切除术和子宫肌瘤栓塞术患者的复发水平，分别。
方法：进行了一项回顾性横断面研究，以比较诊断为子宫肌瘤的女性子宫肌瘤栓塞术和子宫肌瘤切除术之间的复发率和对生活质量的影响。数据来自2009年1月至2021年1月在妇产科诊所以及介入放射学诊所寻求治疗的152名妇女。13名参与者因无法保持联系而被排除在外。该试验包括76例进行子宫肌瘤切除术的患者和63例进行子宫肌瘤栓塞的患者。在这两组中,50名患者的生活质量，手术后五年,使用UFS-QOL测量进行评估。符合条件的参与者是20至40岁的女性，根据FIGO分类，有症状的3-5型肌瘤，而且没有合并症.20岁以下或40岁以上的个人，或那些分类为FIGO类型1,2,6,7,8的肌瘤不包括在内。其他排除标准包括妊娠状态，子宫内膜活检结果异常，异常涂片检查，息肉,癌症,子宫腺肌病和凝血障碍。
结果：通过症状学和诊断放射学方法确定了肌瘤的复发。发现子宫肌瘤切除术患者的复发率为31.6％（n=24），子宫肌瘤栓塞患者的复发率为14.3％（n=9）。两组间差异无统计学意义(p>0.05)。接受子宫肌瘤切除术的组表现出更少的症状，降低焦虑，和更好的身体情绪得分。子宫肌瘤剔除组有较高的平均焦虑评分(p<0.01)。在控制方面没有明显的差异，意识,性功能,或两组之间的总分。与术前相比，术后第一年的症状和焦虑明显减少（p<0.01）。与术前相比，能源,心情,意识,术后第1年和第5年性功能显著改善(p<0.01)。
结论：我们的研究结果表明，与子宫动脉栓塞组相比，子宫肌瘤切除术组的复发率无统计学意义。值得注意的是,子宫肌瘤切除术后症状发生和焦虑的减少在生活质量方面显著有利.虽然栓塞被提供作为一种治疗选择，子宫肌瘤切除术在生活质量方面取得了更有利的结果.
方法：进行了一项回顾性横断面研究，以比较诊断为子宫肌瘤的女性子宫肌瘤栓塞术和子宫肌瘤切除术之间的复发率和对生活质量的影响。数据来自2009年1月至2021年1月在妇产科诊所以及介入放射学诊所寻求治疗的152名妇女。13名参与者因无法保持联系而被排除在外。该试验包括76例进行子宫肌瘤切除术的患者和63例进行子宫肌瘤栓塞的患者。在这两组中,50名患者的生活质量，手术后五年,使用UFS-QOL测量进行评估。符合条件的参与者是20至40岁的女性，根据FIGO分类，有症状的3-5型肌瘤，而且没有合并症.20岁以下或40岁以上的个人，或那些分类为FIGO类型1,2,6,7,8的肌瘤不包括在内。其他排除标准包括妊娠状态，子宫内膜活检结果异常，异常涂片检查，息肉,癌症,子宫腺肌病和凝血障碍。
结果：通过症状学和诊断放射学方法确定了肌瘤的复发。发现子宫肌瘤切除术患者的复发率为31.6％（n=24），子宫肌瘤栓塞患者的复发率为14.3％（n=9）。两组间差异无统计学意义(p>0.05)。接受子宫肌瘤切除术的组表现出更少的症状，降低焦虑，和更好的身体情绪得分。子宫肌瘤剔除组有较高的平均焦虑评分(p<0.01)。在控制方面没有明显的差异，意识,性功能,或两组之间的总分。与术前相比，术后第一年的症状和焦虑明显减少（p<0.01）。与术前相比，能源,心情,意识,术后第1年和第5年性功能显著改善(p<0.01)。
结论：我们的研究结果表明，与子宫动脉栓塞组相比，子宫肌瘤切除术组的复发率无统计学意义。值得注意的是,子宫肌瘤切除术后症状发生和焦虑的减少在生活质量方面显著有利.虽然栓塞被提供作为一种治疗选择，子宫肌瘤切除术在生活质量方面取得了更有利的结果.
