PDF(Pubmed)
Abstract：
The purpose of the present systematic review was to synthesize evidence on associated risk factors of hearing loss (HL) in children. Evidence-based research articles on HL published between January 2013 and December 2022 using PubMed, Cochrane, and Scopus databases were searched. The study included children between zero and three years of age who have permanent bilateral/unilateral HL (BHL/UHL) by employing case-control studies, randomized controlled trials, nonrandomized studies, prospective or retrospective cohort studies, and studies with or without comparison groups. The Newcastle-Ottawa Scale (NOS) and the Joanna Briggs Institute (JBI) critical appraisal checklist for longitudinal and cross-sectional studies were used to rate the quality of the chosen studies. The studies that would be considered were reviewed by two independent authors, and a third author was contacted if there was a dispute. A preliminary literature search uncovered 505 articles from the electronic search and 41 studies by hand searching. Duplicate records were eliminated, leaving 432 records. The abstract and title were read, and 340 studies were eliminated. There were 92 articles in total that qualified for full-text screening. Among these, 75 articles were disregarded since they lacked information or failed to assess the risk factors for HL. The qualitative synthesis, therefore, included 17 articles. Most often, cross-sectional study designs were used in the studies that were reviewed, which were then followed by longitudinal studies. Three of the studies that were reviewed used a prospective cohort design. The quality of all the included studies was rated to be good. The current review revealed that the primary statistically significant risk factors for HL included ventilator support; craniofacial anomalies; low birth weight (LBW); forceps delivery; loop diuretics; meningitis; asphyxia; intensive care; consanguinity; sepsis; Apgar scores between 0 and 4 at one minute; toxoplasmosis, other agents, rubella, cytomegalovirus, and herpes (TORCH) infections; and hyperbilirubinemia.
摘要：
本系统评价的目的是综合有关儿童听力损失（HL）相关危险因素的证据。2013年1月至2022年12月期间使用PubMed发表的关于HL的循证研究文章，科克伦,搜索了Scopus数据库。该研究通过病例对照研究纳入了0至3岁患有永久性双侧/单侧HL（BHL/UHL）的儿童，随机对照试验，非随机研究，前瞻性或回顾性队列研究，以及有或没有比较组的研究。使用纽卡斯尔-渥太华量表（NOS）和乔安娜·布里格斯研究所（JBI）的纵向和横断面研究关键评估清单来评估所选研究的质量。两名独立作者对将要考虑的研究进行了审查，如果有争议，请联系第三位作者。初步的文献检索发现了电子检索中的505篇文章和手工检索中的41篇研究。重复的记录被删除,留下432条记录.阅读了摘要和标题，340项研究被淘汰。共有92篇文章符合全文筛选的条件。其中,由于缺乏信息或未能评估HL的危险因素，因此忽略了75篇文章。定性综合，因此,共17篇文章。大多数情况下,横断面研究设计用于审查的研究中，随后进行了纵向研究。审查的三项研究使用了前瞻性队列设计。所有纳入研究的质量均被评为良好。目前的审查显示，HL的主要具有统计学意义的危险因素包括呼吸机支持;颅面异常;低出生体重（LBW）;产钳分娩;loop利尿剂;脑膜炎;窒息;重症监护;血缘关系;败血症;Apgar评分在一分钟内介于0和4之间;弓形虫病，其他代理人,风疹,巨细胞病毒,和疱疹（TORCH）感染;和高胆红素血症。
