Abstract：
Objective: To explore the effect of vidian neurectomy and selective vidian neurectomy in the treatment of moderate and severe persistent allergic rhinitis (AR). Methods: A total of 60 patients with moderate-to-severe persistent AR treated in Zhejiang Provincial Hospital of Integrated Traditional Chinese and Western Medicine from June 2018 to June 2020 were selected, including 28 males and 32 females. A total of 40 cases in the observation group were subjected to vidianneurectomy, while, 20 cases in the control group underwent selective vidianneurectomy. Patients in the two groups were followed up at 6 months, 1 year, and 2 years, respectively, and evaluated according to AR diagnostic and efficacy assessment criteria. Four symptoms of sneezing, clear runny nose, nasal congestion, and nasal itching were scored as efficacy indices before and at 6 months, 1 year, and 2 years after surgery. The regression of the lower turbinate swelling after surgery was assessed by nasal endoscopy or sinus CT. Postoperative tear secretion was followed up in both groups, and patients with dry eyes were counted in combination with ocular symptoms. SPSS 19.0 software was used to statistically analyze the data before and after the surgery and between the two groups. Results: The preoperative, 6-month, 1-year, and 2-year postoperative inferior turbinate signs were (2.73±0.45), (1.20±0.41), (1.25±0.49) and (1.30±0.56) points in the observation group and (2.75±0.44), (1.45±0.69), (1.75±0.72) and (1.90±0.85) points in the control group, respectively, with a statistically significant difference in the between-subjects effect test between the two groups (F=8.28, P<0.05), indicating a more durable surgical effect in the observation group. The total effective rate at 2 years after surgery was 95.0% (38/40) in the observation group and 50% (10/20) in the control group. The difference between the two groups by Fisher\'s exact test was statistically significant. No dry eye patient was found in either group at a 1.5-year postoperative follow-up. Conclusion: Both vidianneurectomy and selective vidianneurectomy have good recent treatment effects, vidianneurectomy has better long-term curative effects than selective vidianneurectomy.
目的： 探究翼管神经主干切断术和选择性翼管神经分支切断术治疗中重度持续性变应性鼻炎（AR）的效果。 方法： 选取2018年6月至2020年6月于浙江省中西医结合医院接受治疗的中重度持续性AR患者60例，其中男28例，女32例。观察组采用翼管神经主干切断术，共40例；对照组采用翼管神经分支切断术，共20例。分别于术后6个月、1年和2年对两组患者进行近远期疗效随访，参照AR诊断及疗效评定标准进行评价。将术前及术后6个月、1年和2年的喷嚏、流清涕、鼻塞和鼻痒4个症状作为疗效指数进行评分。通过鼻内镜或鼻窦CT评估术后下鼻甲肿胀消退的情况。随访两组患者术后泪液分泌情况，结合眼部症状，对干眼症患者进行计数。采用SPSS 19.0软件对手术前后及两组之间数据进行统计学分析。 结果： 术前、术后6个月、1年和2年的下鼻甲体征在观察组分别为（2.73±0.45）、（1.20±0.41）、（1.25±0.49）和（1.30±0.56）分，对照组分别为（2.75±0.44）、（1.45±0.69）、（1.75±0.72）和（1.90±0.85）分，两组主体间效应检验差异有统计学意义（F=8.28，P<0.05），提示观察组的手术效果更持久。术后2年的总有效率观察组为95.0%（38/40），对照组为50%（10/20）。费希尔精确检验两组之间差异有统计学意义（χ2=16.88，P<0.05）。术后随访1.5年时，两组均未出现干眼症患者。 结论： 翼管神经主干切断术和选择性翼管神经分支切断术均有很好的近期治疗效果，前者较后者具有更好的远期疗效。.
目的： 探究翼管神经主干切断术和选择性翼管神经分支切断术治疗中重度持续性变应性鼻炎（AR）的效果。 方法： 选取2018年6月至2020年6月于浙江省中西医结合医院接受治疗的中重度持续性AR患者60例，其中男28例，女32例。观察组采用翼管神经主干切断术，共40例；对照组采用翼管神经分支切断术，共20例。分别于术后6个月、1年和2年对两组患者进行近远期疗效随访，参照AR诊断及疗效评定标准进行评价。将术前及术后6个月、1年和2年的喷嚏、流清涕、鼻塞和鼻痒4个症状作为疗效指数进行评分。通过鼻内镜或鼻窦CT评估术后下鼻甲肿胀消退的情况。随访两组患者术后泪液分泌情况，结合眼部症状，对干眼症患者进行计数。采用SPSS 19.0软件对手术前后及两组之间数据进行统计学分析。 结果： 术前、术后6个月、1年和2年的下鼻甲体征在观察组分别为（2.73±0.45）、（1.20±0.41）、（1.25±0.49）和（1.30±0.56）分，对照组分别为（2.75±0.44）、（1.45±0.69）、（1.75±0.72）和（1.90±0.85）分，两组主体间效应检验差异有统计学意义（F=8.28，P<0.05），提示观察组的手术效果更持久。术后2年的总有效率观察组为95.0%（38/40），对照组为50%（10/20）。费希尔精确检验两组之间差异有统计学意义（χ2=16.88，P<0.05）。术后随访1.5年时，两组均未出现干眼症患者。 结论： 翼管神经主干切断术和选择性翼管神经分支切断术均有很好的近期治疗效果，前者较后者具有更好的远期疗效。.
摘要：
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