Abstract：
To compare the efficacy of maxillomandibular advancement (MMA) for patients with obstructive sleep apnea (OSA) with class 2 versus 3 dentofacial deformities (DFDs).
Retrospective chart review.
Tertiary sleep surgery center.
Patients with OSA and DFD class 2 versus 3 undergoing MMA at Stanford Sleep Surgery between 2014 and 2021 were matched by preoperative body mass index (BMI), age, and sex. Postoperative outcome was compared with polysomnography measures and patient-reported outcome measures (PROMs).
Twenty-eight matched subjects, 14 in each deformity group were identified and assessed. The mean age (standard deviation) was 34.29 (10.21) and 33.86 (10.23) for classes 2 and 3, respectively. The apnea-hypopnea index (AHI) decreased from 43.42 (28.30) to 9.6 (5.29) (p < .001) and 37.17 (35.77) to 11.81 (15.74) (p = .042) in class 2 and 3 subjects, respectively. The oxygen desaturation index (ODI) changed from 30.48 (24.02) to 6.88 (3.39) (p = .024) and 11.43 (11.40) to 5.44 (7.96) (p = .85) in class 2 and 3 subjects, respectively. The Epworth sleepiness scale changed from 8.93 (5.28) to 3.91 (2.70) (p = .018) and 10.23 (4.38) to 4.22 (3.07) (p = .006) in class 2 and 3 subjects, respectively.
Among age, sex, and BMI-matched subjects, MMA is equally effective in both dentofacial class 2 and 3 groups, both objectively and subjectively. Preoperatively, dentofacial class 2 patients with OSA presented with the more severe disease with higher AHI and ODI. Dentofacial class 3 patients with OSA may require additional attention to improve nasal function outcomes.
Retrospective chart review.
Tertiary sleep surgery center.
Patients with OSA and DFD class 2 versus 3 undergoing MMA at Stanford Sleep Surgery between 2014 and 2021 were matched by preoperative body mass index (BMI), age, and sex. Postoperative outcome was compared with polysomnography measures and patient-reported outcome measures (PROMs).
Twenty-eight matched subjects, 14 in each deformity group were identified and assessed. The mean age (standard deviation) was 34.29 (10.21) and 33.86 (10.23) for classes 2 and 3, respectively. The apnea-hypopnea index (AHI) decreased from 43.42 (28.30) to 9.6 (5.29) (p < .001) and 37.17 (35.77) to 11.81 (15.74) (p = .042) in class 2 and 3 subjects, respectively. The oxygen desaturation index (ODI) changed from 30.48 (24.02) to 6.88 (3.39) (p = .024) and 11.43 (11.40) to 5.44 (7.96) (p = .85) in class 2 and 3 subjects, respectively. The Epworth sleepiness scale changed from 8.93 (5.28) to 3.91 (2.70) (p = .018) and 10.23 (4.38) to 4.22 (3.07) (p = .006) in class 2 and 3 subjects, respectively.
Among age, sex, and BMI-matched subjects, MMA is equally effective in both dentofacial class 2 and 3 groups, both objectively and subjectively. Preoperatively, dentofacial class 2 patients with OSA presented with the more severe disease with higher AHI and ODI. Dentofacial class 3 patients with OSA may require additional attention to improve nasal function outcomes.
摘要：
目的：比较上颌下颌前移术（MMA）治疗阻塞性睡眠呼吸暂停（OSA）伴2级和3级牙颌面畸形（DFDs）的疗效。
方法：回顾性图表回顾。
方法：三级睡眠手术中心。
方法：2014年至2021年在斯坦福睡眠手术中接受MMA的OSA和DFD2级和3级患者与术前体重指数（BMI）相匹配，年龄,和性爱。将术后结果与多导睡眠图测量和患者报告的结果测量（PROM）进行比较。
结果：28个匹配的受试者，对每个畸形组14例进行了鉴定和评估。第2类和第3类的平均年龄（标准偏差）分别为34.29（10.21）和33.86（10.23）。2级和3级受试者的呼吸暂停低通气指数（AHI）从43.42（28.30）降至9.6（5.29）（p<.001），从37.17（35.77）降至11.81（15.74）（p=.042），分别。第2类和第3类受试者的氧去饱和指数（ODI）从30.48（24.02）变为6.88（3.39）（p=.024），从11.43（11.40）变为5.44（7.96）（p=.85），分别。在2级和3级科目中，Epworth嗜睡量表从8.93（5.28）变为3.91（2.70）（p=.018），从10.23（4.38）变为4.22（3.07）（p=.006），分别。
结论：在年龄，性别,和BMI匹配的受试者，MMA在2类和3类牙面组中同样有效，客观和主观。术前,2级OSA患者表现为更严重的疾病，AHI和ODI较高。3级OSA患者可能需要额外注意以改善鼻功能结果。
方法：回顾性图表回顾。
方法：三级睡眠手术中心。
方法：2014年至2021年在斯坦福睡眠手术中接受MMA的OSA和DFD2级和3级患者与术前体重指数（BMI）相匹配，年龄,和性爱。将术后结果与多导睡眠图测量和患者报告的结果测量（PROM）进行比较。
结果：28个匹配的受试者，对每个畸形组14例进行了鉴定和评估。第2类和第3类的平均年龄（标准偏差）分别为34.29（10.21）和33.86（10.23）。2级和3级受试者的呼吸暂停低通气指数（AHI）从43.42（28.30）降至9.6（5.29）（p<.001），从37.17（35.77）降至11.81（15.74）（p=.042），分别。第2类和第3类受试者的氧去饱和指数（ODI）从30.48（24.02）变为6.88（3.39）（p=.024），从11.43（11.40）变为5.44（7.96）（p=.85），分别。在2级和3级科目中，Epworth嗜睡量表从8.93（5.28）变为3.91（2.70）（p=.018），从10.23（4.38）变为4.22（3.07）（p=.006），分别。
结论：在年龄，性别,和BMI匹配的受试者，MMA在2类和3类牙面组中同样有效，客观和主观。术前,2级OSA患者表现为更严重的疾病，AHI和ODI较高。3级OSA患者可能需要额外注意以改善鼻功能结果。
