PDF(Pubmed)
Abstract：
UNASSIGNED: To examine the association between animal contact (primarily dogs and cats) and non-malarial fever, as well as with secondary symptoms of headache, nausea, vomiting, and cough, in 687 children in Greater Accra Region, Ghana.
UNASSIGNED: Cross-sectional study of acute febrile illness among children aged 1-15 years old between October 2016 and August 2017.
UNASSIGNED: Ledzokuku-Krowor Municipal Assembly (LEKMA) Hospital, Teshie, Greater Accra Region.
UNASSIGNED: The study included children with acute fever, defined as a measured temperature of greater than 37.5°C, occurring less than seven days before the hospital visit, and afebrile children as controls.
UNASSIGNED: Measured fever, self-reported fever, and secondary symptoms, each adjusting for patient household characteristics.
UNASSIGNED: Animal contact was neither associated with measured fever (OR = 1.04, 95% CI 0.73-1.49) nor with self-reported fever (OR = 0.97, 95% CI 0.68-1.39). Animal contact was associated with headache (OR = 3.26, 95% CI 2.23-4.77, P < .01) and nausea (OR = 3.05, 95% CI 1.99-4.68, P < .01), but not with vomiting or cough. Additional models that used alternate inclusion criteria to define non-malarial fever yielded similar results. Several bacterial zoonoses that could plausibly have been transmitted by dogs and cats were diagnosed in the study population.
UNASSIGNED: These findings suggest the need for future studies to evaluate animal contact as a risk factor for bacterial zoonoses that may serve as an etiological driver of acute febrile illness.
UNASSIGNED: no external funding.
UNASSIGNED: Cross-sectional study of acute febrile illness among children aged 1-15 years old between October 2016 and August 2017.
UNASSIGNED: Ledzokuku-Krowor Municipal Assembly (LEKMA) Hospital, Teshie, Greater Accra Region.
UNASSIGNED: The study included children with acute fever, defined as a measured temperature of greater than 37.5°C, occurring less than seven days before the hospital visit, and afebrile children as controls.
UNASSIGNED: Measured fever, self-reported fever, and secondary symptoms, each adjusting for patient household characteristics.
UNASSIGNED: Animal contact was neither associated with measured fever (OR = 1.04, 95% CI 0.73-1.49) nor with self-reported fever (OR = 0.97, 95% CI 0.68-1.39). Animal contact was associated with headache (OR = 3.26, 95% CI 2.23-4.77, P < .01) and nausea (OR = 3.05, 95% CI 1.99-4.68, P < .01), but not with vomiting or cough. Additional models that used alternate inclusion criteria to define non-malarial fever yielded similar results. Several bacterial zoonoses that could plausibly have been transmitted by dogs and cats were diagnosed in the study population.
UNASSIGNED: These findings suggest the need for future studies to evaluate animal contact as a risk factor for bacterial zoonoses that may serve as an etiological driver of acute febrile illness.
UNASSIGNED: no external funding.
摘要：
■为了检查动物接触（主要是狗和猫）与非疟疾热之间的关联，以及头痛的次要症状，恶心,呕吐,咳嗽,在大阿克拉地区的687名儿童中，加纳。
■2016年10月至2017年8月期间1-15岁儿童急性高热病的横断面研究。
■Ledzokuku-Krowor市政议会（LEKMA）医院，Teshie,大阿克拉地区。
■这项研究包括患有急性发热的儿童，定义为测量温度大于37.5°C，发生在医院就诊前不到七天，和发热的孩子作为控制。
■发烧，自我报告的发烧，和次要症状，每次针对患者家庭特征进行调整。
■动物接触既不与测量的发热相关（OR=1.04，95％CI0.73-1.49），也不与自我报告的发热相关（OR=0.97，95％CI0.68-1.39）。动物接触与头痛（OR=3.26，95％CI2.23-4.77，P<0.01）和恶心（OR=3.05，95％CI1.99-4.68，P<0.01）有关。但不是呕吐或咳嗽。使用替代纳入标准来定义非疟疾发热的其他模型也产生了类似的结果。在研究人群中诊断出几种可能由狗和猫传播的细菌性人畜共患病。
这些研究结果表明，有必要在未来的研究中评估动物接触是细菌性人畜共患病的危险因素，而细菌性人畜共患病可能是急性发热性疾病的病因驱动因素。
■没有外部资金。
■2016年10月至2017年8月期间1-15岁儿童急性高热病的横断面研究。
■Ledzokuku-Krowor市政议会（LEKMA）医院，Teshie,大阿克拉地区。
■这项研究包括患有急性发热的儿童，定义为测量温度大于37.5°C，发生在医院就诊前不到七天，和发热的孩子作为控制。
■发烧，自我报告的发烧，和次要症状，每次针对患者家庭特征进行调整。
■动物接触既不与测量的发热相关（OR=1.04，95％CI0.73-1.49），也不与自我报告的发热相关（OR=0.97，95％CI0.68-1.39）。动物接触与头痛（OR=3.26，95％CI2.23-4.77，P<0.01）和恶心（OR=3.05，95％CI1.99-4.68，P<0.01）有关。但不是呕吐或咳嗽。使用替代纳入标准来定义非疟疾发热的其他模型也产生了类似的结果。在研究人群中诊断出几种可能由狗和猫传播的细菌性人畜共患病。
这些研究结果表明，有必要在未来的研究中评估动物接触是细菌性人畜共患病的危险因素，而细菌性人畜共患病可能是急性发热性疾病的病因驱动因素。
■没有外部资金。
