PDF(Pubmed)
Abstract：
Malignant melanoma is a highly aggressive disease with a propensity for metastatic spread. Although recent advances in targeted therapies have improved outcomes, effective screening for metastasis remains an important area of further research. We present a case of a man in his 70s who was recently diagnosed with recurrent, locally advanced melanoma. He presented with abdominal fullness, jaundice, and poor appetite. MR imaging of the abdomen revealed innumerable hepatic cysts with internal fluid-fluid levels which were markedly increased in size and number from recent imaging. These findings necessitated a broad differential that included parasitic or bacterial infection, metastases, or drug-induced polycystic liver disease. Subsequent biopsy revealed metastatic melanoma consistent with the patient\'s primary tumor. The patient was ultimately transitioned to comfort care measures due to the burden of the liver metastases and passed away shortly after presentation.
摘要：
恶性黑色素瘤是一种具有转移扩散倾向的高度侵袭性疾病。尽管靶向治疗的最新进展改善了结果，有效的转移筛查仍然是进一步研究的重要领域。我们介绍了一个70多岁的男人最近被诊断患有复发性疾病，局部晚期黑色素瘤。他表现出腹部丰满，黄疸,食欲不振。腹部的MR成像显示，无数的肝囊肿具有内部流体水平，与最近的成像相比，其大小和数量显着增加。这些发现需要广泛的差异，包括寄生虫或细菌感染，转移,或药物诱导的多囊性肝病。随后的活检显示转移性黑色素瘤与患者的原发肿瘤一致。由于肝转移的负担，患者最终过渡到舒适的护理措施，并在就诊后不久去世。
