PDF(Pubmed)
Abstract：
The consumption of foods that are rich in phenolic compounds has chemopreventive effects on many cancers, including breast cancer, ovarian cancer, and endometrial cancer. A wide spectrum of their health-promoting properties such as antioxidant, anti-inflammatory, and anticancer activities, has been demonstrated. This paper analyzes the mechanisms of the anticancer action of selected common flavonols, including kemferol, myricetin, quercetin, fisetin, galangin, isorhamnetin, and morin, in preclinical studies, with particular emphasis on in vitro studies in gynecological cancers and breast cancer. In the future, these compounds may find applications in the prevention and treatment of gynecological cancers and breast cancer, but this requires further, more advanced research.
摘要：
食用富含酚类化合物的食物对许多癌症有化学预防作用，包括乳腺癌,卵巢癌,和子宫内膜癌。它们广泛的健康促进特性，如抗氧化剂，抗炎,和抗癌活动，已经被证明了。本文分析了选定的常见黄酮醇的抗癌作用机制，包括Kemferol,杨梅素,槲皮素,Fisetin,galangin,异鼠李素,还有Morin,在临床前研究中，特别强调妇科癌症和乳腺癌的体外研究。在未来,这些化合物可能在预防和治疗妇科癌症和乳腺癌中找到应用，但这需要进一步，更先进的研究。
