Abstract：
Although higher anterior knee laxity is an established risk factor of ACL injury, underlying mechanisms are uncertain. While decreased proprioception and altered movement patterns in individuals with anterior knee laxity have been identified, the potential impact of higher laxity on brain activity is not well understood. Thus, the purpose of this study is to identify the impact of different magnitudes of knee laxity on brain function during anterior knee joint loading. Twenty-seven healthy and active female college students without any previous severe lower leg injuries volunteered for this study. Anterior knee laxity was measured using a knee arthrometer KT-2000 to assign participants to a higher laxity (N=15) or relatively lower laxity group (N=12). Functional magnetic resonance images were obtained during passive anterior knee joint loading in a task-based design using a 3T MRI scanner. Higher knee laxity individuals demonstrated diminished cortical activation in the left superior parietal lobe during passive anterior knee joint loading. Less brain activation in the regions associated with awareness of bodily movements in females with higher knee laxity may indicate a possible connection between brain activity and knee laxity. The results of this study may help researchers and clinicians develop effective rehabilitation programs for individuals with increased knee laxity. This article is protected by copyright. All rights reserved.
摘要：
尽管较高的前膝松弛是ACL损伤的既定危险因素，潜在的机制是不确定的。虽然已经发现膝关节前松弛患者的本体感觉下降和运动模式改变，尚不清楚松弛对大脑活动的潜在影响。因此，这项研究的目的是确定不同程度的膝关节松弛对大脑功能的影响在膝关节前负荷。27名健康活跃的女大学生自愿参加了这项研究，此前没有任何严重的小腿受伤。使用膝关节分析仪KT-2000测量膝关节前松弛度，将参与者分配到较高松弛度（N=15）或相对较低松弛度的组（N=12）。在基于任务的设计中，使用3TMRI扫描仪在被动前膝关节加载期间获得了功能磁共振图像。在被动的前膝关节负荷期间，较高的膝关节松弛度个体显示左上顶叶的皮质激活减少。在膝关节松弛度较高的女性中，与身体运动意识相关的区域的大脑激活较少，这可能表明大脑活动与膝关节松弛之间存在联系。这项研究的结果可能有助于研究人员和临床医生为膝关节松弛度增加的人制定有效的康复计划。本文受版权保护。保留所有权利。
