Abstract：
OBJECTIVE: This study aimed to describe the level of comprehensive needs among cancer patients treated with immune checkpoint inhibitors, to explore the relationship between comprehensive needs and demographic factors, and to examine the relationship between comprehensive needs and treatment variables.
METHODS: A cross-sectional descriptive study design was adopted. From September 2021 to July 2022, 194 cancer patients treated with immune checkpoint inhibitors were recruited using a convenience sampling method in tertiary teaching hospitals in Zhejiang Province, China. The Comprehensive Needs Assessment Tool for Cancer Patients (CNAT) and questionnaires to assess demographic and clinical characteristics were used to collect data.
RESULTS: The average comprehensive needs score for cancer patients treated with immune checkpoint inhibitors was 39.2 ± 17.2. Patients reported high levels of medical care needs, knowledge information needs, hospital facilities needs and nursing needs but low levels of religious spiritual support needs, psychoemotional needs, actual support needs, and physical symptom needs. Multiple stepwise linear regression showed that age, primary caregivers, cancer type, number of immunotherapy courses and the occurrence of immune-related adverse events (irAEs) were the main factors affecting the comprehensive needs of cancer patients treated with ICIs (p < 0.05).
CONCLUSIONS: Age, primary caregivers, cancer type, number of immunotherapy treatment courses and the occurrence of irAEs are important factors affecting the comprehensive unmet needs of cancer patients treated with immune checkpoint inhibitors. Nurses should perform targeted interventions according to the different situations of patients to improve the quality of care.
METHODS: A cross-sectional descriptive study design was adopted. From September 2021 to July 2022, 194 cancer patients treated with immune checkpoint inhibitors were recruited using a convenience sampling method in tertiary teaching hospitals in Zhejiang Province, China. The Comprehensive Needs Assessment Tool for Cancer Patients (CNAT) and questionnaires to assess demographic and clinical characteristics were used to collect data.
RESULTS: The average comprehensive needs score for cancer patients treated with immune checkpoint inhibitors was 39.2 ± 17.2. Patients reported high levels of medical care needs, knowledge information needs, hospital facilities needs and nursing needs but low levels of religious spiritual support needs, psychoemotional needs, actual support needs, and physical symptom needs. Multiple stepwise linear regression showed that age, primary caregivers, cancer type, number of immunotherapy courses and the occurrence of immune-related adverse events (irAEs) were the main factors affecting the comprehensive needs of cancer patients treated with ICIs (p < 0.05).
CONCLUSIONS: Age, primary caregivers, cancer type, number of immunotherapy treatment courses and the occurrence of irAEs are important factors affecting the comprehensive unmet needs of cancer patients treated with immune checkpoint inhibitors. Nurses should perform targeted interventions according to the different situations of patients to improve the quality of care.
摘要：
目的：本研究旨在描述接受免疫检查点抑制剂治疗的癌症患者的综合需求水平，探索综合需求与人口因素之间的关系，并考察综合需求与治疗变量之间的关系。
方法：采用横断面描述性研究设计。2021年9月至2022年7月，在浙江省三级教学医院采用便利抽样方法，招募了194例接受免疫检查点抑制剂治疗的癌症患者，中国。癌症患者综合需求评估工具（CNAT）和评估人口统计学和临床特征的问卷用于收集数据。
结果：接受免疫检查点抑制剂治疗的癌症患者的平均综合需求评分为39.2±17.2。患者报告了高水平的医疗护理需求，知识信息需求，医院设施需求和护理需求，但宗教精神支持需求水平较低，心理情感需求，实际支持需求，和身体症状需要。多元逐步线性回归显示，年龄，主要照顾者,癌症类型,免疫治疗疗程数和免疫相关不良事件（irAEs）的发生是影响ICIs治疗癌症患者综合需求的主要因素（p<0.05）。
结论：年龄，主要照顾者,癌症类型,免疫治疗疗程数和irAE的发生是影响接受免疫检查点抑制剂治疗的癌症患者的综合未满足需求的重要因素。护士应根据患者的不同情况进行有针对性的干预,以提高护理质量。
方法：采用横断面描述性研究设计。2021年9月至2022年7月，在浙江省三级教学医院采用便利抽样方法，招募了194例接受免疫检查点抑制剂治疗的癌症患者，中国。癌症患者综合需求评估工具（CNAT）和评估人口统计学和临床特征的问卷用于收集数据。
结果：接受免疫检查点抑制剂治疗的癌症患者的平均综合需求评分为39.2±17.2。患者报告了高水平的医疗护理需求，知识信息需求，医院设施需求和护理需求，但宗教精神支持需求水平较低，心理情感需求，实际支持需求，和身体症状需要。多元逐步线性回归显示，年龄，主要照顾者,癌症类型,免疫治疗疗程数和免疫相关不良事件（irAEs）的发生是影响ICIs治疗癌症患者综合需求的主要因素（p<0.05）。
结论：年龄，主要照顾者,癌症类型,免疫治疗疗程数和irAE的发生是影响接受免疫检查点抑制剂治疗的癌症患者的综合未满足需求的重要因素。护士应根据患者的不同情况进行有针对性的干预,以提高护理质量。
