We recruited 133 children with ARS between January 2020 and January 2022 from our hospital. Sinus secretion were collected and cultured for Gram stain as well as antimicrobial susceptibility tests.
Moraxella catarrhalis, Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae and Pseudomonas aeruginosa were detected in order in children with ARS, of which 25% were negative for bacterial culture and 10% were positive for two strains. Amoxicillin and clavulanate potassium were useful for Haemophilus influenzae, Streptococcus pneumoniae and Moraxella catarrhalis. Quinolones are useful for Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae and Pseudomonas aeruginosa.
This research updates the proportion of ARS bacterial infection in children in southern China and the antibiotic sensitivity.
方法:我们在2020年1月至2022年1月期间从我们医院招募了133名患有ARS的儿童。收集鼻窦分泌物并培养用于革兰氏染色以及抗微生物药敏试验。
结果:卡他莫拉氏菌,金黄色葡萄球菌,流感嗜血杆菌,在ARS患儿中依次检测肺炎链球菌和铜绿假单胞菌,其中25%为细菌培养阴性,10%为2株阳性。阿莫西林和克拉维酸钾对流感嗜血杆菌有用,肺炎链球菌和卡他莫拉菌。喹诺酮类药物对金黄色葡萄球菌有用,流感嗜血杆菌,肺炎链球菌和铜绿假单胞菌。
结论:本研究更新了中国南方地区儿童ARS细菌感染的比例和抗生素敏感性。