关键词: Bowel management Chronic idiopathic constipation Enema Megarectum Senna

Mesh : Child Humans Retrospective Studies Constipation / diagnostic imaging therapy Sennosides / therapeutic use Polyethylene Glycols / therapeutic use Enema Megacolon Colon, Sigmoid Treatment Outcome

来  源:   DOI:10.1007/s00383-023-05508-9

Abstract:
OBJECTIVE: This study aimed to analyze our radiologically supervised bowel management program (RS-BMP) outcomes in patients with chronic idiopathic constipation (CIC).
METHODS: A retrospective study was conducted. We included all patients with CIC who participated in our RS-BMP at Children´s Hospital Colorado from July 2016 to October 2022.
RESULTS: Eighty patients were included. The average time with constipation was 5.6 years. Before our RS-BMP, 95% had received non-radiologically supervised treatments, and 71% had attempted two or more treatments. Overall, 90% had tried Polyethylene Glycol and 43% Senna. Nine patients had a history of Botox injections. Five underwent anterograde continence procedure, and one a sigmoidectomy. Behavioral disorders (BD) were found in 23%. At the end of the RS-BMP, 96% of patients had successful outcomes, 73% were on Senna, and 27% were on enemas. Megarectum was detected in 93% of patients with successful outcomes and 100% with unsuccessful outcomes (p = 0.210). Of the patients with BD, 89% had successful outcomes, and 11% had unsuccessful.
CONCLUSIONS: Our RS-BMP has been proven to be effective in treating CIC. The radiologically supervised use of Senna and enemas was the appropriate treatment in 96% of the patients. BD and megarectum were associated with unsuccessful outcomes.
摘要:
目的:本研究旨在分析慢性特发性便秘(CIC)患者的放射学监督肠管理计划(RS-BMP)结果。
方法:进行回顾性研究。我们纳入了2016年7月至2022年10月在科罗拉多州儿童医院参加RS-BMP的所有CIC患者。
结果:纳入80例患者。便秘的平均时间为5.6年。在我们的RS-BMP之前,95%的人接受了非放射学监督治疗,71%曾尝试过两种或两种以上的治疗.总的来说,90%的人尝试过聚乙二醇和43%的塞纳。9名患者有肉毒杆菌素注射史。五人接受了顺行失禁手术,还有一个是乙状结肠切除术.23%的人发现了行为障碍(BD)。在RS-BMP结束时,96%的患者有成功的结果,73%的人在塞纳,27%在灌肠。在93%的患者中检测到大直肠,结果成功,100%的患者结果不成功(p=0.210)。BD患者中,89%有成功的结果,11%的人没有成功。
结论:我们的RS-BMP已被证明可有效治疗CIC。在96%的患者中,在放射学监督下使用塞纳和灌肠剂是适当的治疗方法。BD和大直肠与不成功的结果相关。
公众号