PDF(Pubmed)
Abstract：
Worldwide, up to a quarter of all recognized pregnancies result in Early Pregnancy Loss (EPL), also known as miscarriage. For many women, this is a traumatic experience that leads to persistent negative mental health responses. The most common morbidity reported in studies from different countries is complicated grief, usually comorbid with depression, anxiety, and Post-Traumatic Stress Disorder (PTSD). To our best knowledge, no studies characterizing the psychological impact of EPL have been made in Portugal.
An online survey was conducted to evaluate clinical symptoms of perinatal grief, anxiety, depression, and PTSD in women who suffered a spontaneous loss within 20 weeks of gestation. Out of 1,015 women who answered this survey, 873 were considered eligible, and subsequently distributed in 7 groups according to the time passed between their loss and their participation in the study.
The proportion of women showing symptoms of all comorbidities was greater in those whose loss had happened within a month, and there was a significant gradual decrease over time in scores and proportions of clinical perinatal grief and PTSD. In terms of depression symptoms, scores dropped significantly in the group whose loss occurred 13-24 months before their participation but proportions oscillated without great changes in the other groups. Regarding anxiety, there were small oscillations, but there was no significant decrease of symptoms over time.
Overall, despite a general drop in scores for most morbidities over time, substantial proportions of women showed persistent symptoms of clinical morbidities 3 years or more after the loss. Therefore, it is essential to promote monitoring of possible complicated responses to the event, to provide appropriate and timely intervention to those women in need.
An online survey was conducted to evaluate clinical symptoms of perinatal grief, anxiety, depression, and PTSD in women who suffered a spontaneous loss within 20 weeks of gestation. Out of 1,015 women who answered this survey, 873 were considered eligible, and subsequently distributed in 7 groups according to the time passed between their loss and their participation in the study.
The proportion of women showing symptoms of all comorbidities was greater in those whose loss had happened within a month, and there was a significant gradual decrease over time in scores and proportions of clinical perinatal grief and PTSD. In terms of depression symptoms, scores dropped significantly in the group whose loss occurred 13-24 months before their participation but proportions oscillated without great changes in the other groups. Regarding anxiety, there were small oscillations, but there was no significant decrease of symptoms over time.
Overall, despite a general drop in scores for most morbidities over time, substantial proportions of women showed persistent symptoms of clinical morbidities 3 years or more after the loss. Therefore, it is essential to promote monitoring of possible complicated responses to the event, to provide appropriate and timely intervention to those women in need.
摘要：
■全球，所有公认的妊娠中有多达四分之一导致早孕丢失（EPL），也被称为流产。对很多女人来说,这是一种创伤经历，导致持续的负面心理健康反应。来自不同国家的研究报告中最常见的发病率是复杂的悲伤，通常与抑郁症并存，焦虑,创伤后应激障碍（PTSD）。据我们所知，在葡萄牙，没有研究描述EPL的心理影响。
■进行了一项在线调查，以评估围产期悲伤的临床症状，焦虑,抑郁症,和PTSD在妊娠20周内自发丧失的妇女。在回答这项调查的1015名女性中，873被认为是合格的，随后根据他们失去和参与研究之间的时间分为7组。
出现所有合并症症状的女性比例在一个月内发生损失的女性中更大，随着时间的推移，临床围产期悲伤和PTSD的得分和比例显着逐渐下降。在抑郁症状方面，在参与前13~24个月出现失学的组中,得分显著下降,但在其他组中,失学比例出现振荡,但无较大变化.关于焦虑，有小的振荡，但随着时间的推移，症状没有明显减轻。
■总的来说，尽管随着时间的推移，大多数发病率的分数普遍下降，相当比例的女性在失药后3年或更长时间表现出持续的临床症状。因此,必须促进对事件可能的复杂反应的监测，为有需要的妇女提供适当和及时的干预。
■进行了一项在线调查，以评估围产期悲伤的临床症状，焦虑,抑郁症,和PTSD在妊娠20周内自发丧失的妇女。在回答这项调查的1015名女性中，873被认为是合格的，随后根据他们失去和参与研究之间的时间分为7组。
出现所有合并症症状的女性比例在一个月内发生损失的女性中更大，随着时间的推移，临床围产期悲伤和PTSD的得分和比例显着逐渐下降。在抑郁症状方面，在参与前13~24个月出现失学的组中,得分显著下降,但在其他组中,失学比例出现振荡,但无较大变化.关于焦虑，有小的振荡，但随着时间的推移，症状没有明显减轻。
■总的来说，尽管随着时间的推移，大多数发病率的分数普遍下降，相当比例的女性在失药后3年或更长时间表现出持续的临床症状。因此,必须促进对事件可能的复杂反应的监测，为有需要的妇女提供适当和及时的干预。
