PDF(Pubmed)
Abstract：
The outbreak of coronavirus disease 2019 (COVID-19), which was originated from a severe acute respiratory syndrome-coronavirus-2 (SARS-COV-2) infection, has become an international public health emergency. The aim of this study was to assess the clinical symptoms and physical findings in both hypertensive and nonhypertensive patients infected with COVID-19.
UNASSIGNED: A retrospective observational case-control study with diagnosis of COVID-19 by laboratory-confirmed test was conducted on 280 consecutive unselected patients. This was a single-center study. The demographics, laboratory, and clinical findings data were extracted from the hospital registry database.
UNASSIGNED: Of our 280 patients in the study, there were 149 men (53%) and 138 (50%) were older than 60 years (mean=67.75), and also 50 in-hospital deaths occurred (mortality rate, 17%). Total 19(6.9%) were taking opioid, and smoking. There were no significant differences in the rate of fever, cough, sputum production, gastrointestinal symptoms, myalgia, and headache in the both hypertensive and nonhypertensive groups. The prevalence of underlying diseases was significantly higher in older patients in comparison with younger ones (P=0<0.05), COVID-19 mortality was noticed to be higher among hypertensive patients as compared with nonhypertensive patients (P=0<0.05).
UNASSIGNED: Hypertension is associated with a poor prognosis and higher mortality among COVID-19 patients. Optimizing blood pressure is essential during the management of COVID-19. Our research implies the importance of early care and education of old patient with hypertension and other comorbidities.
UNASSIGNED: A retrospective observational case-control study with diagnosis of COVID-19 by laboratory-confirmed test was conducted on 280 consecutive unselected patients. This was a single-center study. The demographics, laboratory, and clinical findings data were extracted from the hospital registry database.
UNASSIGNED: Of our 280 patients in the study, there were 149 men (53%) and 138 (50%) were older than 60 years (mean=67.75), and also 50 in-hospital deaths occurred (mortality rate, 17%). Total 19(6.9%) were taking opioid, and smoking. There were no significant differences in the rate of fever, cough, sputum production, gastrointestinal symptoms, myalgia, and headache in the both hypertensive and nonhypertensive groups. The prevalence of underlying diseases was significantly higher in older patients in comparison with younger ones (P=0<0.05), COVID-19 mortality was noticed to be higher among hypertensive patients as compared with nonhypertensive patients (P=0<0.05).
UNASSIGNED: Hypertension is associated with a poor prognosis and higher mortality among COVID-19 patients. Optimizing blood pressure is essential during the management of COVID-19. Our research implies the importance of early care and education of old patient with hypertension and other comorbidities.
摘要：
2019年冠状病毒病爆发（COVID-19），它起源于严重的急性呼吸道综合症-冠状病毒-2（SARS-COV-2）感染，已成为国际突发公共卫生事件。这项研究的目的是评估感染COVID-19的高血压和非高血压患者的临床症状和身体状况。
■对280名连续未选择的患者进行了一项回顾性观察性病例对照研究，通过实验室确认的测试诊断为COVID-19。这是一项单中心研究。人口统计，实验室,和临床发现数据从医院登记数据库中提取.
■在我们的280名患者中，有149名男性（53％）和138名（50％）年龄超过60岁（平均=67.75），还有50例住院死亡(死亡率，17%）。共有19人（6.9%）服用阿片类药物，和吸烟。发热率无显著差异,咳嗽,痰液生产，胃肠道症状,肌痛，高血压和非高血压组的头痛。老年患者基础疾病患病率明显高于年轻患者(P=0<0.05),COVID-19在高血压患者中的死亡率高于非高血压患者(P=0<0.05)。
■高血压与COVID-19患者的不良预后和较高的死亡率相关。在COVID-19的管理过程中，优化血压至关重要。我们的研究暗示了对患有高血压和其他合并症的老年患者进行早期护理和教育的重要性。
■对280名连续未选择的患者进行了一项回顾性观察性病例对照研究，通过实验室确认的测试诊断为COVID-19。这是一项单中心研究。人口统计，实验室,和临床发现数据从医院登记数据库中提取.
■在我们的280名患者中，有149名男性（53％）和138名（50％）年龄超过60岁（平均=67.75），还有50例住院死亡(死亡率，17%）。共有19人（6.9%）服用阿片类药物，和吸烟。发热率无显著差异,咳嗽,痰液生产，胃肠道症状,肌痛，高血压和非高血压组的头痛。老年患者基础疾病患病率明显高于年轻患者(P=0<0.05),COVID-19在高血压患者中的死亡率高于非高血压患者(P=0<0.05)。
■高血压与COVID-19患者的不良预后和较高的死亡率相关。在COVID-19的管理过程中，优化血压至关重要。我们的研究暗示了对患有高血压和其他合并症的老年患者进行早期护理和教育的重要性。
