关键词: Asia Delphi expert consensus lobectomy non–small cell lung cancer segmentectomy sublobar resection

来  源:   DOI:10.1016/j.xjon.2023.03.013   PDF(Pubmed)

Abstract:
UNASSIGNED: Segmentectomy as a parenchymal-sparing surgical approach has been recommended over lobectomy in select patients with early-stage non-small cell lung cancer. This study aimed to address 3 aspects of segmentectomy (\"patient indication\"; \"segmentectomy approaches\"; \"lymph node assessment\") where there is limited clinical guidance.
UNASSIGNED: A modified Delphi approach comprising 3 anonymous surveys and 2 expert discussions was used to establish consensus on the aforementioned topics among 15 thoracic surgeons (2 Steering Committee; 2 Task Force; 11 Voting Experts) from Asia who have extensive segmentectomy experience. Statements were developed by the Steering Committee and Task Force based on their clinical experience, published literature (rounds 1-3), and comments received from Voting Experts through surveys (rounds 2-3). Voting Experts indicated their agreement with each statement on a 5-point Likert scale. Consensus was defined as ≥70% of Voting Experts selecting either \"Agree\"/\"Strongly Agree\" or \"Disagree\"/\"Strongly Disagree.\"
UNASSIGNED: Consensus from the 11 Voting Experts was reached on 36 statements (11 \"patient indication\" statements; 19 \"segmentation approaches\" statements; 6 \"lymph node assessment\" statements). In rounds 1, 2, and 3, consensus was reached on 48%, 81%, and 100% of drafted statements, respectively.
UNASSIGNED: A recent phase 3 trial reported significantly improved 5-year overall survival rates for segmentectomy compared with lobectomy, proposing thoracic surgeons to consider segmentectomy as a surgical option in suitable patients. This consensus serves as a guidance to thoracic surgeons considering segmentectomy in patients with early non-small cell lung cancer, outlining key principles that surgeons should consider in surgical decision-making.
摘要:
在选择早期非小细胞肺癌患者的肺叶切除术中,作为保留实质的手术方法,建议采用分段切除术。本研究旨在解决临床指导有限的节段切除术的3个方面(“患者适应症”;“节段切除术方法”;“淋巴结评估”)。
采用改良的Delphi方法,包括3次匿名调查和2次专家讨论,在来自亚洲的15名胸外科医师(2个指导委员会;2个工作组;11名投票专家)中就上述主题达成共识。陈述由督导委员会及专责小组根据其临床经验制订,已出版文献(第1-3轮),以及通过调查(第2-3轮)从投票专家那里收到的评论。投票专家表示,他们同意李克特5分制的每项声明。共识被定义为≥70%的投票专家选择“同意”/“强烈同意”或“不同意”/“强烈不同意”。
11位投票专家就36项陈述达成共识(11项“患者适应症”陈述;19项“分段方法”陈述;6项“淋巴结评估”陈述)。在第1轮、第2轮和第3轮中,达成了48%的共识,81%,和100%起草的声明,分别。
最近的一项3期试验报道,与肺叶切除术相比,肺段切除术的5年总生存率显著提高,建议胸外科医师考虑将节段切除术作为合适患者的手术选择。这一共识为胸外科医师考虑对早期非小细胞肺癌患者进行肺段切除术提供了指导。概述外科医生在手术决策中应考虑的关键原则。
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