PDF(Pubmed)
Abstract：
UNASSIGNED: To study and compare the demographic and clinical profile of acute ocular burns (AOB) in children and adults.
UNASSIGNED: This retrospective case series included 271 children (338 eyes) and 1300 adults (1809 eyes) who presented to two tertiary eye care centers within one month of sustaining AOB. Data regarding demographics, causative agents, severity of injury, visual acuity (VA), and treatment were collected and analyzed.
UNASSIGNED: Males were more commonly affected particularly among adults (81% versus 64%, P < 0.00001). Among children, 79% sustained domestic injuries, whereas 59% of adults had work-place injuries (P < 0.0001). Most cases were due to alkali (38%) and acids (22%). Edible lime (chuna, 32%), superglue (14%), and firecrackers (12%) in children, and chuna (7%), insecticides, lye, superglue (6% each), toilet cleaner (4%) and battery acid (3%) in adults, were the main causative agents. The percentage of cases with Dua grade IV-VI was greater in children (16% versus 9%; P = 0.0001). Amniotic membrane grafting and/or tarsorrhaphy were needed in 36% and 14% of affected eyes in children and adults, respectively (P < 0.00001). The median presenting VA was logMAR 0.5 in children and logMAR 0.3 in adults (P = 0.0001), which improved significantly with treatment in both groups (P < 0.0001), but the final VA in eyes with Dua grade IV-VI burns was poorer in children (logMAR 1.3 versus logMAR 0.8, P = 0.04).
UNASSIGNED: The findings clearly delineate the at-risk groups, causative agents, clinical severity, and treatment outcomes of AOB. Increased awareness and data-driven targeted preventive strategies are needed to reduce the avoidable ocular morbidity in AOB.
UNASSIGNED: This retrospective case series included 271 children (338 eyes) and 1300 adults (1809 eyes) who presented to two tertiary eye care centers within one month of sustaining AOB. Data regarding demographics, causative agents, severity of injury, visual acuity (VA), and treatment were collected and analyzed.
UNASSIGNED: Males were more commonly affected particularly among adults (81% versus 64%, P < 0.00001). Among children, 79% sustained domestic injuries, whereas 59% of adults had work-place injuries (P < 0.0001). Most cases were due to alkali (38%) and acids (22%). Edible lime (chuna, 32%), superglue (14%), and firecrackers (12%) in children, and chuna (7%), insecticides, lye, superglue (6% each), toilet cleaner (4%) and battery acid (3%) in adults, were the main causative agents. The percentage of cases with Dua grade IV-VI was greater in children (16% versus 9%; P = 0.0001). Amniotic membrane grafting and/or tarsorrhaphy were needed in 36% and 14% of affected eyes in children and adults, respectively (P < 0.00001). The median presenting VA was logMAR 0.5 in children and logMAR 0.3 in adults (P = 0.0001), which improved significantly with treatment in both groups (P < 0.0001), but the final VA in eyes with Dua grade IV-VI burns was poorer in children (logMAR 1.3 versus logMAR 0.8, P = 0.04).
UNASSIGNED: The findings clearly delineate the at-risk groups, causative agents, clinical severity, and treatment outcomes of AOB. Increased awareness and data-driven targeted preventive strategies are needed to reduce the avoidable ocular morbidity in AOB.
摘要：
■研究和比较儿童和成人急性眼烧伤（AOB）的人口统计学和临床特征。
■这个回顾性病例系列包括271名儿童（338只眼）和1300名成人（1809只眼），他们在维持AOB后的一个月内到两个三级眼部护理中心就诊。有关人口统计的数据，病原体，损伤的严重程度,视敏度（VA），收集和分析治疗方法。
■男性更常受到影响，尤其是在成年人中（81%对64%，P<0.00001)。在儿童中，79%的人遭受家庭伤害，而59%的成年人有工作场所伤害(P<0.0001)。大多数病例是由于碱（38％）和酸（22％）。食用石灰（chuna，32%），强力胶（14%），和儿童鞭炮（12%），和Chuna(7%)，杀虫剂,碱液,强力胶（每个6%），成人的厕所清洁剂（4％）和电池酸（3％），是主要的病原体。儿童DuaIV-VI级病例的百分比更高（16％对9％；P=0.0001）。36％和14％的儿童和成人受影响的眼睛需要羊膜移植和/或tarsorraphhy，分别(P<0.00001)。儿童的VA中位数为logMAR0.5，成人为logMAR0.3（P=0.0001），两组均有明显改善(P<0.0001),但是儿童DuaIV-VI级烧伤的最终VA较差（logMAR1.3对logMAR0.8，P=0.04）。
■这些发现清楚地描述了风险群体，病原体，临床严重程度，以及AOB的治疗结果。需要提高意识和数据驱动的针对性预防策略，以减少AOB可避免的眼部发病率。
■这个回顾性病例系列包括271名儿童（338只眼）和1300名成人（1809只眼），他们在维持AOB后的一个月内到两个三级眼部护理中心就诊。有关人口统计的数据，病原体，损伤的严重程度,视敏度（VA），收集和分析治疗方法。
■男性更常受到影响，尤其是在成年人中（81%对64%，P<0.00001)。在儿童中，79%的人遭受家庭伤害，而59%的成年人有工作场所伤害(P<0.0001)。大多数病例是由于碱（38％）和酸（22％）。食用石灰（chuna，32%），强力胶（14%），和儿童鞭炮（12%），和Chuna(7%)，杀虫剂,碱液,强力胶（每个6%），成人的厕所清洁剂（4％）和电池酸（3％），是主要的病原体。儿童DuaIV-VI级病例的百分比更高（16％对9％；P=0.0001）。36％和14％的儿童和成人受影响的眼睛需要羊膜移植和/或tarsorraphhy，分别(P<0.00001)。儿童的VA中位数为logMAR0.5，成人为logMAR0.3（P=0.0001），两组均有明显改善(P<0.0001),但是儿童DuaIV-VI级烧伤的最终VA较差（logMAR1.3对logMAR0.8，P=0.04）。
■这些发现清楚地描述了风险群体，病原体，临床严重程度，以及AOB的治疗结果。需要提高意识和数据驱动的针对性预防策略，以减少AOB可避免的眼部发病率。
