PDF(Pubmed)
Abstract：
UNASSIGNED: The main objective of this study is to establish the characteristics of blood laboratory parameters in hospitalized coronavirus disease 2019 (COVID-19) Ukrainian patients and the significance of the above-mentioned parameters for predicting the course of the disease.
UNASSIGNED: Hematocytological, biochemical, and hemostasis methods of research have been used. Groups of patients with different forms of the coronavirus disease course have been analyzed (lethality - recovery, recovery with a severe and mild course).
UNASSIGNED: Age is one of the risk factors for COVID-19 mortality. Absolute values of neutrophils, neutrophil-lymphocyte ratio (NLR), systemic inflammation index, d-dimer, C-reactive protein, and soluble fibrin complex can be used by clinicians to effectively differentiate between two possible outcomes (lethality vs. recovery). A higher number of stab leukocytes, d-NLR, and platelets concentration have been recorded in patients with severe COVID-19 cases, compared to mild ones. The risk of adverse COVID-19 outcome (lethality) is significantly linked with d-dimer and NLR (odds ratio 1.42). The risk of a severe course of the disease was significantly associated with the count of leukocytes (odds ratio 4.96).
UNASSIGNED: Hematocytological, biochemical, and hemostasis methods of research have been used. Groups of patients with different forms of the coronavirus disease course have been analyzed (lethality - recovery, recovery with a severe and mild course).
UNASSIGNED: Age is one of the risk factors for COVID-19 mortality. Absolute values of neutrophils, neutrophil-lymphocyte ratio (NLR), systemic inflammation index, d-dimer, C-reactive protein, and soluble fibrin complex can be used by clinicians to effectively differentiate between two possible outcomes (lethality vs. recovery). A higher number of stab leukocytes, d-NLR, and platelets concentration have been recorded in patients with severe COVID-19 cases, compared to mild ones. The risk of adverse COVID-19 outcome (lethality) is significantly linked with d-dimer and NLR (odds ratio 1.42). The risk of a severe course of the disease was significantly associated with the count of leukocytes (odds ratio 4.96).
摘要：
■这项研究的主要目的是建立住院冠状病毒病2019（COVID-19）乌克兰患者的血液实验室参数特征以及上述参数对预测病程的意义。
■血液细胞学，生物化学，和止血方法的研究已经使用。对具有不同形式的冠状病毒病程的患者组进行了分析(致死率-恢复，严重和温和的过程中恢复)。
■年龄是COVID-19死亡的危险因素之一。中性粒细胞的绝对值，中性粒细胞-淋巴细胞比率（NLR），全身炎症指数,D-二聚体,C反应蛋白,临床医生可以使用可溶性纤维蛋白复合物来有效区分两种可能的结果(致死率与recovery).更多的刺伤白细胞，d-NLR,并记录了重症COVID-19患者的血小板浓度，与温和的相比。COVID-19不良结局(致死率)的风险与d-二聚体和NLR显著相关(比值比1.42)。严重病程的风险与白细胞计数显着相关（比值比4.96）。
■血液细胞学，生物化学，和止血方法的研究已经使用。对具有不同形式的冠状病毒病程的患者组进行了分析(致死率-恢复，严重和温和的过程中恢复)。
■年龄是COVID-19死亡的危险因素之一。中性粒细胞的绝对值，中性粒细胞-淋巴细胞比率（NLR），全身炎症指数,D-二聚体,C反应蛋白,临床医生可以使用可溶性纤维蛋白复合物来有效区分两种可能的结果(致死率与recovery).更多的刺伤白细胞，d-NLR,并记录了重症COVID-19患者的血小板浓度，与温和的相比。COVID-19不良结局(致死率)的风险与d-二聚体和NLR显著相关(比值比1.42)。严重病程的风险与白细胞计数显着相关（比值比4.96）。
