UNASSIGNED: Articles for this paper were obtained by reviewing the literature related to the role of AIF in metabolic diseases on PubMed. The search terms included the following: \"apoptosis\", \"metabolism\" or \"metabolic diseases\" plus \"apoptosis-inducing factor\". The titles, abstracts, and full texts of relevant English-language publications published from October 1996 to June 2022 were manually screened to clarify the role of AIF in metabolic diseases.
UNASSIGNED: We found that AIF played an important role in a variety of metabolically-related diseases, such as diabetes, obesity, metabolic syndrome, and tumor metabolism, by mediating apoptosis.
UNASSIGNED: We summarized the important role of AIF in a variety of metabolic diseases, which might help to further expand the understanding of AIF and to develop AIF-related therapeutic targets.
■本文的文章是通过回顾PubMed上有关AIF在代谢疾病中的作用的文献而获得的。搜索词包括:“凋亡”,“代谢”或“代谢疾病”加“凋亡诱导因子”。标题,摘要,我们对1996年10月至2022年6月出版的相关英文出版物的全文进行了手动筛选,以阐明AIF在代谢性疾病中的作用.
■我们发现AIF在多种代谢相关疾病中起着重要作用,比如糖尿病,肥胖,代谢综合征,和肿瘤代谢,通过介导细胞凋亡。
■我们总结了AIF在多种代谢性疾病中的重要作用,这可能有助于进一步扩大对AIF的理解和开发AIF相关的治疗靶点。