PDF(Pubmed)
Abstract：
UNASSIGNED: This study provides a comprehensive overview of the management of postoperative vasospasm after skull base surgeries. This phenomenon is rare but can be of serious sequelae.
UNASSIGNED: Medline, Embase, and PubMed Central were searched, along with examining the references of the included studies. Only case reports and series that reported vasospasm following a skull base pathology were incorporated. Cases with pathologies other than skull base, subarachnoid hemorrhage, aneurysm, and reversible cerebral vasoconstriction syndrome were excluded from the study. Quantitative data were presented as mean (Standard Deviation) or median (range), accordingly, while qualitative data were presented as frequency (percentage). Chi- square test and one-way analysis of variance were used to assess for any association between the different factors and patient outcomes.
UNASSIGNED: We had a total of 42 cases extracted from the literature. The mean age was 40.1 (±16.1) with approximately equal males and females (19 [45.2%] and 23 [54.8%], respectively). The time to develop vasospasm after the surgery was 7 days (±3.7). Most of the cases were diagnosed by either angiogram or magnetic resonance angiography. Seventeen of the 42 patients had pituitary adenoma as the pathology. Anterior circulation was nearly affected in all patients. For management, most patients received pharmacological with supportive management. Twenty-three patients had an incomplete recovery as a result of vasospasm.
UNASSIGNED: Vasospasm following skull base operations can affect males and females, and most patients in this review were middle-aged adults. The outcome of patients varies; however, most patients did not achieve a full recovery. There was no correlation between any factors and the outcome.
UNASSIGNED: Medline, Embase, and PubMed Central were searched, along with examining the references of the included studies. Only case reports and series that reported vasospasm following a skull base pathology were incorporated. Cases with pathologies other than skull base, subarachnoid hemorrhage, aneurysm, and reversible cerebral vasoconstriction syndrome were excluded from the study. Quantitative data were presented as mean (Standard Deviation) or median (range), accordingly, while qualitative data were presented as frequency (percentage). Chi- square test and one-way analysis of variance were used to assess for any association between the different factors and patient outcomes.
UNASSIGNED: We had a total of 42 cases extracted from the literature. The mean age was 40.1 (±16.1) with approximately equal males and females (19 [45.2%] and 23 [54.8%], respectively). The time to develop vasospasm after the surgery was 7 days (±3.7). Most of the cases were diagnosed by either angiogram or magnetic resonance angiography. Seventeen of the 42 patients had pituitary adenoma as the pathology. Anterior circulation was nearly affected in all patients. For management, most patients received pharmacological with supportive management. Twenty-three patients had an incomplete recovery as a result of vasospasm.
UNASSIGNED: Vasospasm following skull base operations can affect males and females, and most patients in this review were middle-aged adults. The outcome of patients varies; however, most patients did not achieve a full recovery. There was no correlation between any factors and the outcome.
摘要：
■本研究全面概述了颅底手术后血管痉挛的处理方法。这种现象很少见，但可能有严重的后遗症。
■Medline，Embase,并搜查了PubMedCentral,同时检查纳入研究的参考文献。仅纳入报告颅底病理后血管痉挛的病例报告和系列。颅底以外的病理病例，蛛网膜下腔出血,动脉瘤,和可逆性脑血管收缩综合征被排除在研究之外。定量数据以平均值(标准偏差)或中值(范围)表示，因此,而定性数据以频率（百分比）表示。使用卡方检验和单向方差分析来评估不同因素与患者结果之间的任何关联。
■我们从文献中提取了42例病例。平均年龄为40.1（±16.1），男女大致相等（19[45.2％]和23[54.8％]，分别)。手术后发生血管痉挛的时间为7天（±3.7）。大多数病例是通过血管造影或磁共振血管造影诊断的。42例患者中有17例以垂体腺瘤为病理。所有患者的前循环几乎都受到影响。对于管理，大多数患者接受药物支持治疗.23例患者由于血管痉挛而恢复不完全。
■颅底手术后的血管痉挛会影响男性和女性，本综述中大多数患者为中年人.患者的结果各不相同；然而，大多数患者没有完全康复.任何因素与结果之间均无相关性。
■Medline，Embase,并搜查了PubMedCentral,同时检查纳入研究的参考文献。仅纳入报告颅底病理后血管痉挛的病例报告和系列。颅底以外的病理病例，蛛网膜下腔出血,动脉瘤,和可逆性脑血管收缩综合征被排除在研究之外。定量数据以平均值(标准偏差)或中值(范围)表示，因此,而定性数据以频率（百分比）表示。使用卡方检验和单向方差分析来评估不同因素与患者结果之间的任何关联。
■我们从文献中提取了42例病例。平均年龄为40.1（±16.1），男女大致相等（19[45.2％]和23[54.8％]，分别)。手术后发生血管痉挛的时间为7天（±3.7）。大多数病例是通过血管造影或磁共振血管造影诊断的。42例患者中有17例以垂体腺瘤为病理。所有患者的前循环几乎都受到影响。对于管理，大多数患者接受药物支持治疗.23例患者由于血管痉挛而恢复不完全。
■颅底手术后的血管痉挛会影响男性和女性，本综述中大多数患者为中年人.患者的结果各不相同；然而，大多数患者没有完全康复.任何因素与结果之间均无相关性。
