Abstract：
To identify (i) the prevalence of meeting the endpoints of \'stable periodontitis\' (probing pocket depth [PPD] ≤ 4 mm, bleeding on probing [BoP] < 10%, no BoP at 4 mm sites), \'endpoints of therapy\' (no PPD > 4 mm with BoP, no PPD ≥ 6 mm), \'controlled periodontitis\' (≤4 sites with PPD ≥ 5 mm), \'PPD < 5 mm\' and \'PPD < 6 mm\' at the start of supportive periodontal care [SPC]) and (ii) the incidence of tooth loss in relation to not meeting these endpoints within a minimum of 5 years of SPC.
Systematic electronic and manual searches were conducted to identify studies where subjects, upon completion of active periodontal therapy, entered into SPC. Duplicate screening was performed to find relevant articles. Corresponding authors were contacted to confirm inclusion and retrieve required clinical data for further analyses to assess the prevalence of reaching endpoints and incidence of subsequent tooth loss, if available, within at least 5 years of SPC. Meta-analyses were carried out to evaluate risk ratios for tooth loss in relation to not reaching the various endpoints.
Fifteen studies including 12,884 patients and 323,111 teeth were retrieved. Achievement of endpoints at baseline SPC was rare (1.35%, 11.00% and 34.62%, respectively, for \'stable periodontitis\', \'endpoints of therapy\' and \'controlled periodontitis\'). Less than a third of the 1190 subjects with 5 years of SPC data lost teeth-a total of 3.14% of all teeth were lost. Statistically significant associations with tooth loss, at the subject-level, were found for not achieving \'controlled periodontitis\' (relative risk [RR] = 2.57), PPD < 5 mm (RR = 1.59) and PPD < 6 mm (RR = 1.98).
An overwhelming majority of subjects and teeth do not achieve the proposed endpoints for periodontal stability, yet most periodontal patients preserve most of their teeth during an average of 10-13 years in SPC.
Systematic electronic and manual searches were conducted to identify studies where subjects, upon completion of active periodontal therapy, entered into SPC. Duplicate screening was performed to find relevant articles. Corresponding authors were contacted to confirm inclusion and retrieve required clinical data for further analyses to assess the prevalence of reaching endpoints and incidence of subsequent tooth loss, if available, within at least 5 years of SPC. Meta-analyses were carried out to evaluate risk ratios for tooth loss in relation to not reaching the various endpoints.
Fifteen studies including 12,884 patients and 323,111 teeth were retrieved. Achievement of endpoints at baseline SPC was rare (1.35%, 11.00% and 34.62%, respectively, for \'stable periodontitis\', \'endpoints of therapy\' and \'controlled periodontitis\'). Less than a third of the 1190 subjects with 5 years of SPC data lost teeth-a total of 3.14% of all teeth were lost. Statistically significant associations with tooth loss, at the subject-level, were found for not achieving \'controlled periodontitis\' (relative risk [RR] = 2.57), PPD < 5 mm (RR = 1.59) and PPD < 6 mm (RR = 1.98).
An overwhelming majority of subjects and teeth do not achieve the proposed endpoints for periodontal stability, yet most periodontal patients preserve most of their teeth during an average of 10-13 years in SPC.
摘要：
目的：确定（i）达到“稳定性牙周炎”终点的患病率（探查袋深度[PPD]≤4mm，探查出血[BoP]<10%,4mm位置处无BoP),'治疗终点'(使用BoP时无PPD>4mm,无PPD≥6mm)，“控制牙周炎”（≤4个部位，PPD≥5mm），牙周支持性护理开始时的“PPD<5mm”和“PPD<6mm”[SPC]）和（ii）与在至少5年内未达到这些终点有关的牙齿脱落发生率SPC年。
方法：进行了系统的电子和人工搜索，以确定研究对象，完成主动牙周治疗后，进入SPC。重复筛选查找相关文章。联系了相应的作者，以确认纳入并检索所需的临床数据进行进一步分析，以评估达到终点的患病率和随后的牙齿脱落的发生率。如果可用，在SPC至少5年内。进行荟萃分析以评估与未达到各个终点相关的牙齿脱落风险比。
结果：共检索了15项研究，包括12,884例患者和323,111颗牙齿。在基线SPC时达到终点的情况很少见(1.35%，11.00%和34.62%，分别,对于“稳定的牙周炎”，“治疗终点”和“控制牙周炎”)。在具有5年SPC数据的1190名受试者中，不到三分之一的牙齿丢失-总共有3.14％的牙齿丢失。与牙齿脱落有统计学意义的关联，在学科层面，发现未达到“控制牙周炎”（相对风险[RR]=2.57），PPD<5mm(RR=1.59)和PPD<6mm(RR=1.98)。
结论：绝大多数受试者和牙齿没有达到牙周稳定性的建议终点，然而，大多数牙周患者在SPC的平均10-13年内保留了大部分牙齿。
方法：进行了系统的电子和人工搜索，以确定研究对象，完成主动牙周治疗后，进入SPC。重复筛选查找相关文章。联系了相应的作者，以确认纳入并检索所需的临床数据进行进一步分析，以评估达到终点的患病率和随后的牙齿脱落的发生率。如果可用，在SPC至少5年内。进行荟萃分析以评估与未达到各个终点相关的牙齿脱落风险比。
结果：共检索了15项研究，包括12,884例患者和323,111颗牙齿。在基线SPC时达到终点的情况很少见(1.35%，11.00%和34.62%，分别,对于“稳定的牙周炎”，“治疗终点”和“控制牙周炎”)。在具有5年SPC数据的1190名受试者中，不到三分之一的牙齿丢失-总共有3.14％的牙齿丢失。与牙齿脱落有统计学意义的关联，在学科层面，发现未达到“控制牙周炎”（相对风险[RR]=2.57），PPD<5mm(RR=1.59)和PPD<6mm(RR=1.98)。
结论：绝大多数受试者和牙齿没有达到牙周稳定性的建议终点，然而，大多数牙周患者在SPC的平均10-13年内保留了大部分牙齿。
