关键词: Clinical trials Hidradenitis suppurativa Systemic Topical Treatment

来  源:   DOI:10.1007/s13555-023-00956-6   PDF(Pubmed)

Abstract:
Hidradenitis suppurativa (HS) is an oftentimes debilitating condition that presents with painful nodules, abscesses, and sinus tracts. This condition is challenging to treat, in part because the pathogenesis of the condition is incompletely understood but also because there are limited therapeutic options. HS research is undergoing explosive growth with multiple new molecular pathways under study, which will hopefully lead to improved disease control for patients. Part I of this review will provide an overview of the emerging topical and systemic therapies under investigation for HS.
摘要:
化脓性汗腺炎(HS)通常是一种使人衰弱的疾病,表现为痛性结节,脓肿,和窦道。这种情况很难治疗,部分原因是该疾病的发病机制尚未完全了解,也是因为治疗选择有限。HS研究正在经历爆炸性增长,多种新的分子途径正在研究中,这有望改善患者的疾病控制。本综述的第一部分将概述正在研究的HS新兴的局部和全身疗法。
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