控制异质 T 细胞耗竭的层次转录网络及其对免疫检查点阻断的影响。
关键词: PD-1 T cell exhaustion T cell factor 1 TOX chronic TCR stimulation heterogeneous immune checkpoint blockade
Mesh : Humans Immune Checkpoint Inhibitors / pharmacology therapeutic use Gene Regulatory Networks T-Cell Exhaustion T-Lymphocytes Gene Expression Regulation Neoplasms / genetics therapy
来 源:
DOI:10.3389/fimmu.2023.1198551
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