关键词: Ethics Macaque Marmoset Regulations Requirements Welfare

来  源:   DOI:10.1016/j.crneur.2023.100079   PDF(Pubmed)

Abstract:
As science and technology evolve, there is an increasing need for promotion of international scientific exchange. Collaborations, while offering substantial opportunities for scientists and benefit to society, also present challenges for those working with animal models, such as non-human primates (NHPs). Diversity in regulation of animal research is sometimes mistaken for the absence of common international welfare standards. Here, the ethical and regulatory protocols for 13 countries that have guidelines in place for biomedical research involving NHPs were assessed with a focus on neuroscience. Review of the variability and similarity in trans-national NHP welfare regulations extended to countries in Asia, Europe and North America. A tabulated resource was established to advance solution-oriented discussions and scientific collaborations across borders. Our aim is to better inform the public and other stakeholders. Through cooperative efforts to identify and analyze information with reference to evidence-based discussion, the proposed key ingredients may help to shape and support a more informed, open framework. This framework and resource can be expanded further for biomedical research in other countries.
摘要:
随着科学技术的发展,越来越需要促进国际科学交流。合作,在为科学家提供大量机会并造福社会的同时,也给那些使用动物模型的人带来了挑战,例如非人灵长类动物(NHP)。动物研究法规的多样性有时被误认为缺乏共同的国际福利标准。这里,对13个国家的伦理和监管方案进行了评估,这些国家制定了涉及NHP的生物医学研究指南,重点是神经科学.审查跨国NHP福利法规扩展到亚洲国家的可变性和相似性,欧洲和北美。建立了一个列表资源,以推进面向解决方案的讨论和跨境科学合作。我们的目标是更好地告知公众和其他利益相关者。通过合作努力,参考循证讨论来识别和分析信息,拟议的关键成分可能有助于塑造和支持更知情的,开放框架。这一框架和资源可以进一步扩大,用于其他国家的生物医学研究。
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