PDF(Pubmed)
Abstract：
UNASSIGNED: This study aims to investigate the correlation between sleep duration and all-cause and cardiovascular mortality in the general population.
UNASSIGNED: A total of 26,977 participants aged ≥18 years were included in the analysis from the National Health and Nutrition Examination Survey (NHANES) database covering the period from 2005 to 2014. Data on cardiovascular and all-cause deaths were collected until December 2019. Sleep duration was assessed using a structured questionnaire, and participants were categorized into five groups based on their reported sleep duration (≤5, 6, 7, 8, or ≥9 h). Kaplan-Meier survival curves were employed to examine the mortality rates across different sleep duration groups. Multivariate Cox regression models were utilized to explore the association between sleep duration and mortality. Additionally, a restricted cubic spline regression model was employed to identify the non-linear relationship between sleep duration and all-cause and cardiovascular mortality.
UNASSIGNED: The average age of participants was 46.23 ± 18.48 years, with 49.9% of the subjects being male. Over a median follow-up period of 9.42 years, 3,153 (11.7%) participants died from all-cause mortality, among which 819 (3.0%) were attributed to cardiovascular causes. The groups with sleep durations of ≥9 and ≤5 h exhibited the lowest cumulative survival rates for all-cause mortality and cardiovascular mortality, respectively. When using a sleep duration of 7 h as the reference, the hazard ratios (with 95% confidence intervals) for all-cause mortality were 1.28 (1.14-1.44) for ≤5 h, 1.10 (0.98-1.23) for 6 h, 1.21 (1.10-1.34) for 8 h, and 1.53 (1.35-1.73) for ≥9 h. The hazard ratios (with 95% confidence intervals) for cardiovascular mortality were 1.32 (1.04-1.67) for ≤5 h, 1.22 (0.97-1.53) for 6 h, 1.29 (1.05-1.59) for 8 h, and 1.74 (1.37-2.21) for ≥9 h. A U-shaped non-linear relationship between sleep duration and all-cause and cardiovascular mortality was observed, with inflection point thresholds at 7.32 and 7.04 h, respectively.
UNASSIGNED: The findings suggest that the risk of all-cause and cardiovascular mortality is minimized when sleep duration is approximately 7 h.
UNASSIGNED: A total of 26,977 participants aged ≥18 years were included in the analysis from the National Health and Nutrition Examination Survey (NHANES) database covering the period from 2005 to 2014. Data on cardiovascular and all-cause deaths were collected until December 2019. Sleep duration was assessed using a structured questionnaire, and participants were categorized into five groups based on their reported sleep duration (≤5, 6, 7, 8, or ≥9 h). Kaplan-Meier survival curves were employed to examine the mortality rates across different sleep duration groups. Multivariate Cox regression models were utilized to explore the association between sleep duration and mortality. Additionally, a restricted cubic spline regression model was employed to identify the non-linear relationship between sleep duration and all-cause and cardiovascular mortality.
UNASSIGNED: The average age of participants was 46.23 ± 18.48 years, with 49.9% of the subjects being male. Over a median follow-up period of 9.42 years, 3,153 (11.7%) participants died from all-cause mortality, among which 819 (3.0%) were attributed to cardiovascular causes. The groups with sleep durations of ≥9 and ≤5 h exhibited the lowest cumulative survival rates for all-cause mortality and cardiovascular mortality, respectively. When using a sleep duration of 7 h as the reference, the hazard ratios (with 95% confidence intervals) for all-cause mortality were 1.28 (1.14-1.44) for ≤5 h, 1.10 (0.98-1.23) for 6 h, 1.21 (1.10-1.34) for 8 h, and 1.53 (1.35-1.73) for ≥9 h. The hazard ratios (with 95% confidence intervals) for cardiovascular mortality were 1.32 (1.04-1.67) for ≤5 h, 1.22 (0.97-1.53) for 6 h, 1.29 (1.05-1.59) for 8 h, and 1.74 (1.37-2.21) for ≥9 h. A U-shaped non-linear relationship between sleep duration and all-cause and cardiovascular mortality was observed, with inflection point thresholds at 7.32 and 7.04 h, respectively.
UNASSIGNED: The findings suggest that the risk of all-cause and cardiovascular mortality is minimized when sleep duration is approximately 7 h.
摘要：
■本研究旨在调查普通人群中睡眠持续时间与全因死亡率和心血管死亡率之间的相关性。
■共有26,977名年龄≥18岁的参与者被纳入2005年至2014年国家健康和营养调查（NHANES）数据库的分析。截至2019年12月，收集了心血管疾病和全因死亡的数据。使用结构化问卷评估睡眠时间，参与者根据报告的睡眠时间(≤5,6,7,8或≥9h)分为5组.采用Kaplan-Meier存活曲线来检查不同睡眠持续时间组的死亡率。利用多因素Cox回归模型来探讨睡眠持续时间与死亡率之间的关系。此外,我们采用限制性三次样条回归模型来确定睡眠时间与全因死亡率和心血管死亡率之间的非线性关系.
■参与者的平均年龄为46.23±18.48岁，49.9%的受试者是男性。在9.42年的中位随访期内，3,153名（11.7%）参与者死于全因死亡率，其中819例(3.0%)归因于心血管原因.睡眠时间≥9小时和≤5小时组的全因死亡率和心血管死亡率的累积生存率最低。分别。当使用7小时的睡眠持续时间作为参考时，在≤5小时内，全因死亡率的风险比（95%置信区间）为1.28（1.14-1.44），1.10(0.98-1.23)持续6小时，1.21(1.10-1.34)持续8小时，和1.53（1.35-1.73）≥9小时。心血管死亡率的风险比（具有95％置信区间）≤5小时为1.32（1.04-1.67），1.22（0.97-1.53）持续6小时，1.29(1.05-1.59)持续8小时,和1.74（1.37-2.21）≥9小时。观察到睡眠持续时间与全因死亡率和心血管死亡率之间的U形非线性关系，拐点阈值在7.32和7.04h，分别。
■研究结果表明，当睡眠时间约为7小时时，全因死亡和心血管死亡的风险降至最低。
■共有26,977名年龄≥18岁的参与者被纳入2005年至2014年国家健康和营养调查（NHANES）数据库的分析。截至2019年12月，收集了心血管疾病和全因死亡的数据。使用结构化问卷评估睡眠时间，参与者根据报告的睡眠时间(≤5,6,7,8或≥9h)分为5组.采用Kaplan-Meier存活曲线来检查不同睡眠持续时间组的死亡率。利用多因素Cox回归模型来探讨睡眠持续时间与死亡率之间的关系。此外,我们采用限制性三次样条回归模型来确定睡眠时间与全因死亡率和心血管死亡率之间的非线性关系.
■参与者的平均年龄为46.23±18.48岁，49.9%的受试者是男性。在9.42年的中位随访期内，3,153名（11.7%）参与者死于全因死亡率，其中819例(3.0%)归因于心血管原因.睡眠时间≥9小时和≤5小时组的全因死亡率和心血管死亡率的累积生存率最低。分别。当使用7小时的睡眠持续时间作为参考时，在≤5小时内，全因死亡率的风险比（95%置信区间）为1.28（1.14-1.44），1.10(0.98-1.23)持续6小时，1.21(1.10-1.34)持续8小时，和1.53（1.35-1.73）≥9小时。心血管死亡率的风险比（具有95％置信区间）≤5小时为1.32（1.04-1.67），1.22（0.97-1.53）持续6小时，1.29(1.05-1.59)持续8小时,和1.74（1.37-2.21）≥9小时。观察到睡眠持续时间与全因死亡率和心血管死亡率之间的U形非线性关系，拐点阈值在7.32和7.04h，分别。
■研究结果表明，当睡眠时间约为7小时时，全因死亡和心血管死亡的风险降至最低。
