Abstract：
Objective: The current study was carried out to evaluate the effects of laser and Systemp.desensitizer therapy. Further, scanning electron microscopy (SEM) was used to determine the effects of individual or combined desensitizers on human dentinal tubules. Background: The most common clinical condition that makes people uncomfortable is dentin hypersensitivity (DH). Both lasers and drugs that reduce sensitivity have been used to treat DH. Materials and methods: A total of 100 dentinal samples were taken from newly extracted third molars (affected) and divided into 10 groups (A to J), that is, control (A); Systemp.desensitizer (B); diode laser (980 nm) (C); Nd:YAG laser (D); Er:YAG laser (E); Er,Cr:YSGG laser (F); Systemp.desensitizer + diode laser (G); Systemp.desensitizer + Nd:YAG laser (H); Systemp.desensitizer + Er:YAG laser (I); and Systemp.desensitizer + Er,Cr:YSGG laser (J). SEM was used to evaluate the dentinal specimens in each group (longitudinal and transverse portions), and then images of each sample were captured (20 images/sample). In addition, the number of open dentinal tubules was counted and then the occlusion depth in dentinal tubules was measured. Mann-Whitney and Kruskal-Wallis tests were employed to analyze the obtained data. Results: All treatment procedures and protocols were effective in blocking dentinal tubules (p < 0.05). Compared with the other groups, dentinal tubules in the laser and laser combination therapy groups were significantly obstructed (p < 0.05). Diode and Nd:YAG lasers with or without Systemp.desensitizer showed significantly more tubule occlusion and greater sealing depth than Er:YAG and Er,Cr:YSGG lasers with or without Systemp.desensitizer (p < 0.05). Conclusions: In summary, lasers alone or in combination can play a significant role in occluding the dentinal tubules. However, combining the diode or Nd:YAG laser with Systemp.desensitizers is a more effective treatment strategy and may have immediate and long-lasting effects.
摘要：
目的：进行当前研究以评估激光和Systemp的效果。脱敏剂治疗。Further,扫描电子显微镜（SEM）用于确定单个或组合的脱敏剂对人牙本质小管的影响。背景：最常见的让人不舒服的临床状况是牙本质过敏（DH）。激光和降低敏感性的药物均已用于治疗DH。材料和方法：从新提取的第三磨牙（受影响）中抽取总共100个牙本质样品，分为10组（A至J），也就是说,控制(A)；系统。减敏剂(B);二极管激光器(980nm)(C);Nd:YAG激光器(D);Er:YAG激光器(E);Er,Cr:YSGG激光器(F);Systemp.减敏剂+二极管激光器(G);Systemp.脱敏剂+Nd:YAG激光器(H);Systemp.脱敏剂+Er:YAG激光器(I);和Systemp.脱敏剂+Er,Cr:YSGG激光器(J)。SEM用于评估每组（纵向和横向部分）的牙本质标本，然后捕获每个样品的图像(20个图像/样品)。此外,计数开放牙本质小管的数量，然后测量牙本质小管的闭塞深度。采用Mann-Whitney和Kruskal-Wallis检验来分析获得的数据。结果：所有治疗程序和方案均有效阻断牙本质小管（p<0.05）。与其他组相比，激光和激光联合治疗组的牙本质小管明显阻塞（p<0.05）。带或不带Systemp的二极管和Nd:YAG激光器。脱敏剂显示出比Er：YAG和Er明显更多的小管闭塞和更大的密封深度，Cr:具有或不具有Systemp的YSGG激光器。脱敏剂(p<0.05)。结论：总之，激光单独或联合使用可以在阻塞牙本质小管中发挥重要作用。然而,结合二极管或Nd：YAG激光器与Systemp。脱敏剂是一种更有效的治疗策略，可能具有即时和持久的效果。
